INT192023

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.86
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RYR2) transmembrane transport (RYR2)
Anatomy Link Frequency
heart 1
RYR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 10 76.08 Quite High
Catecholamine 2 30.08 Quite Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arrhythmogenic Right Ventricular Dysplasia 90 100.00 Very High Very High Very High
Disease 38 96.92 Very High Very High Very High
Cataract 2 88.32 High High
Adhesions 10 79.52 Quite High
Apoptosis 10 76.96 Quite High
Death 2 63.44 Quite High
Sudden Death 4 61.92 Quite High
Heart Rate Under Development 14 60.72 Quite High
Congenital Anomalies 6 53.92 Quite High
Syndrome 2 26.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduction of the ARVC6 critical interval will improve the feasibility of the identification of the disease causing gene.


Negative_regulation (Reduction) of ARVC6 associated with disease
1) Confidence 0.15 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1444927 Disease Relevance 0.79 Pain Relevance 0.04
Recently, a serendipitous mouse model of ARVC was discovered in which a functional laminin 1 receptor (lamr1) retroposon interacted with heterochromatin protein 1 (HP1) to cause degeneration of cardiomyocytes in the right ventricle of the heart [6].
Negative_regulation (discovered) of ARVC in heart associated with arrhythmogenic right ventricular dysplasia
2) Confidence 0.13 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1444927 Disease Relevance 1.08 Pain Relevance 0

General Comments

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