INT19206

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Context Info
Confidence 0.62
First Reported 1991
Last Reported 2003
Negated 2
Speculated 1
Reported most in Abstract
Documents 5
Total Number 7
Disease Relevance 0.58
Pain Relevance 2.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OXTR) signal transducer activity (OXTR)
Anatomy Link Frequency
myometrium 2
uterus 2
OXTR (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 27 100.00 Very High Very High Very High
opiate 12 100.00 Very High Very High Very High
Analgesic 3 94.72 High High
analgesia 4 89.76 High High
addiction 2 89.52 High High
Dismenorea 6 87.72 High High
noradrenaline 1 83.04 Quite High
cva 1 44.00 Quite Low
Disease Link Frequency Relevance Heat
Dysmenorrhea 4 87.72 High High
Reprotox - General 1 2 81.44 Quite High
Emergencies 3 65.12 Quite High
Cv General 3 Under Development 1 44.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: Taken together, our data demonstrate that the dynamics of oxytocin receptor expression can be affected by stimulation with 17-beta-estradiol and oxytocin not only in the pregnant uterus, but also in the nonpregnant uterus.
Regulation (affected) of Gene_expression (expression) of oxytocin in uterus
1) Confidence 0.62 Published 2003 Journal Arch. Gynecol. Obstet. Section Body Doc Link 14605818 Disease Relevance 0 Pain Relevance 0
This study was designed to investigate the effect of an opiate (5 mg of morphine) given to the mother on the fetal production of oxytocin in labour. 2.
Spec (investigate) Regulation (effect) of Gene_expression (production) of oxytocin associated with opiate and morphine
2) Confidence 0.62 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0.07 Pain Relevance 0.89
Effects of morphine administration on the fetal production of oxytocin in labour.
Regulation (Effects) of Gene_expression (production) of oxytocin associated with morphine
3) Confidence 0.62 Published 1998 Journal Clin. Sci. Section Title Doc Link 9662490 Disease Relevance 0.06 Pain Relevance 0.81
The results demonstrate that fetal production of oxytocin is not influenced by general anaesthesia, thus enabling comparison of labour and nonlabour samples at caesarean section.
Neg (not) Regulation (influenced) of Gene_expression (production) of oxytocin
4) Confidence 0.62 Published 1999 Journal Br J Obstet Gynaecol Section Abstract Doc Link 10609728 Disease Relevance 0 Pain Relevance 0.09
Fetal oxytocin production was not affected by the maternal administration of morphine in the first stage of labour.
Neg (not) Regulation (affected) of Gene_expression (production) of oxytocin associated with morphine
5) Confidence 0.54 Published 1998 Journal Clin. Sci. Section Abstract Doc Link 9662490 Disease Relevance 0.07 Pain Relevance 0.69
Therefore, in the present study we investigated in the nonpregnant myometrium if oxytocin receptor expression can be affected by 17-beta-estradiol and oxytocin stimulation.
Regulation (affected) of Gene_expression (expression) of oxytocin in myometrium
6) Confidence 0.45 Published 2003 Journal Arch. Gynecol. Obstet. Section Abstract Doc Link 14605818 Disease Relevance 0.08 Pain Relevance 0.13
They regulate formation of gap junctions, influx of calcium ions, synthesis of oxytocin, adrenergic receptors and of prostaglandins and cyclic nucleotides.
Regulation (regulate) of Gene_expression (synthesis) of oxytocin
7) Confidence 0.45 Published 1991 Journal Ann. Acad. Med. Singap. Section Abstract Doc Link 2029168 Disease Relevance 0.31 Pain Relevance 0.35

General Comments

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