INT192236

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.59
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90aa1) protein folding (Hsp90aa1) cytosol (Hsp90aa1)
ATPase activity (Hsp90aa1) intracellular (Hsp90aa1) response to stress (Hsp90aa1)
Anatomy Link Frequency
artery endothelium 2
Hsp90aa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 55.08 Quite High
Pain 1 54.56 Quite High
midbrain 8 49.12 Quite Low
Potency 1 41.72 Quite Low
Hippocampus 4 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Thalamus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 99.04 Very High Very High Very High
Muscular Atrophy 1 80.16 Quite High
Shock 15 69.12 Quite High
Cataract 1 57.68 Quite High
Mycobacterium Infection 1 56.96 Quite High
INFLAMMATION 5 55.08 Quite High
Vasculitis 2 53.52 Quite High
Clinical Trials And Case Reports 1 50.00 Quite Low
Systemic Lupus Erythematosus 3 48.12 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 47.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hspabp, thought to be a tumor suppressor, is important for Hsp70 function by mediating its interaction with Hsp90 [86].
Positive_regulation (mediating) of Hsp90 Binding (interaction) of associated with cancer
1) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2965669 Disease Relevance 0.36 Pain Relevance 0
NO is also instrumental in promoting Ang1-induced angiogenesis in combination with HSP90 and Akt in coronary artery endothelium [12].
Positive_regulation (induced) of HSP90 Binding (combination) of in artery endothelium
2) Confidence 0.05 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1456963 Disease Relevance 0.23 Pain Relevance 0.08

General Comments

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