INT192238

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Context Info
Confidence 0.21
First Reported 2006
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NOS3) aging (NOS3) Golgi apparatus (NOS3)
mitochondrion organization (NOS3) cytoplasm (NOS3) cytosol (NOS3)
NOS3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 7 59.68 Quite High
Pain 1 59.16 Quite High
Potency 2 46.32 Quite Low
palliative 1 24.96 Low Low
cytokine 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 94.64 High High
Diabetes Mellitus 6 77.40 Quite High
Cancer 74 71.52 Quite High
Vascular Disease 1 71.12 Quite High
Mycobacterium Infection 1 61.56 Quite High
INFLAMMATION 10 59.68 Quite High
Vasculitis 2 58.12 Quite High
Breast Cancer 2 54.80 Quite High
Systemic Lupus Erythematosus 3 52.72 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 52.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EPCs by a mechanism independent of eNOS [94]; however, further studies based on
Neg (independent) Positive_regulation (independent) of Localization (mechanism) of eNOS
1) Confidence 0.21 Published 2008 Journal PPAR Research Section Body Doc Link PMC2366048 Disease Relevance 0.30 Pain Relevance 0
Recent publications suggest that endothelial-derived NO is required for Ang1-induced angiogenesis and that the PI3-kinase signaling mediates the activation of eNOS and NO release in response to Ang1 [11].
Positive_regulation (mediates) of Neg (NO) Localization (release) of eNOS
2) Confidence 0.07 Published 2006 Journal BMC Cell Biol Section Body Doc Link PMC1456963 Disease Relevance 0.46 Pain Relevance 0.09

General Comments

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