INT192277

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (C15orf55) cytoplasm (C15orf55)
Anatomy Link Frequency
testis 1
C15orf55 (Homo sapiens)
Pain Link Frequency Relevance Heat
epidural 8 71.64 Quite High
backache 4 39.60 Quite Low
vincristine 4 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 40 92.56 High High
Cancer 76 91.24 High High
Bone Cancer 4 80.84 Quite High
Disease Progression 4 74.24 Quite High
Sarcoma 12 72.96 Quite High
Low Back Pain 4 39.60 Quite Low
Weight Loss 4 38.40 Quite Low
Hot Flashes 4 37.12 Quite Low
Superior Vena Cava Syndrome 16 18.00 Low Low
Pressure And Volume Under Development 12 14.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, as variant NUT-rearrangements have been described [4], FISH techniques that detect both BRD4-NUT fusions and variant NUT-rearrangements should also be considered.
Gene_expression (detect) of NUT
1) Confidence 0.44 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1456975 Disease Relevance 0.55 Pain Relevance 0
However, as variant NUT-rearrangements have been described [4], FISH techniques that detect both BRD4-NUT fusions and variant NUT-rearrangements should also be considered.
Gene_expression (fusions) of NUT
2) Confidence 0.44 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1456975 Disease Relevance 0.54 Pain Relevance 0
We herein describe, in detail, the laboratory methods by which the BRD4-NUT -rearrangement can be detected.



Gene_expression (detected) of NUT
3) Confidence 0.39 Published 2006 Journal BMC Cancer Section Abstract Doc Link PMC1456975 Disease Relevance 0.59 Pain Relevance 0.04
BRD4 (bromodomain containing 4) is a bromodomain protein with an important role in cell cycle regulation inhibiting cell cycle progression from G1 to S, whereas NUT (nuclear protein in testis) is a protein of unknown function, normally only expressed in testis tissue [3].
Gene_expression (expressed) of NUT in testis
4) Confidence 0.34 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1456975 Disease Relevance 0.39 Pain Relevance 0

General Comments

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