INT192292

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (IL1B) cell-cell signaling (IL1B) signal transducer activity (OR5A1)
cytosol (IL1B) extracellular space (IL1B) signal transduction (IL1B)
Anatomy Link Frequency
chondrocytes 1
OR5A1 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 37.36 Quite Low
Inflammation 22 8.88 Low Low
Arthritis 10 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Acupuncture 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Onset of action 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 74.24 Quite High
Arthropathy 6 73.44 Quite High
INFLAMMATION 19 8.88 Low Low
Arthritis 11 5.00 Very Low Very Low Very Low
Osteoarthritis 7 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar results to these described in cartilage explants were noted in cultured chondrocytes, where RNI 249, vincaria and the combination reduced IL-1?
RNI 249 Negative_regulation (reduced) of IL-1 in chondrocytes
1) Confidence 0.01 Published 2006 Journal BMC Complement Altern Med Section Body Doc Link PMC1456997 Disease Relevance 0.15 Pain Relevance 0

General Comments

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