INT1923

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Context Info
Confidence 0.41
First Reported 1979
Last Reported 2010
Negated 3
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 7.36
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CEACAM7)
Anatomy Link Frequency
thyroid 1
colon 1
CEACAM7 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 4 97.84 Very High Very High Very High
Angina 1 78.48 Quite High
cytokine 39 70.76 Quite High
imagery 29 48.16 Quite Low
Inflammation 15 5.00 Very Low Very Low Very Low
Pain 15 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 458 100.00 Very High Very High Very High
Adenocarcinoma 10 99.98 Very High Very High Very High
Recurrence 59 99.90 Very High Very High Very High
Disease 70 99.52 Very High Very High Very High
Embolism 7 99.48 Very High Very High Very High
Fowlpox 3 99.28 Very High Very High Very High
Thyroid Neoplasm 6 99.18 Very High Very High Very High
Injury 214 98.60 Very High Very High Very High
Colon Cancer 73 98.46 Very High Very High Very High
Advanced Or Metastatic Breast Cancer 3 97.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
He underwent transrectal and transurethral biopsy of the prostate, which revealed adenocarcinoma positive for CEA and chromogranin A.
Regulation (positive) of CEA associated with adenocarcinoma
1) Confidence 0.41 Published 2007 Journal Int. J. Urol. Section Abstract Doc Link 17302572 Disease Relevance 0.44 Pain Relevance 0.10
Histologically, two types of adenocarcinoma were involved in both primary prostate and metastatic sites: one was a poorly differentiated adenocarcinoma positive for PSA and PAP but not CEA or CA19-9, and the other one was a less differentiated adenocarcinoma partially positive for CEA and CA19-9 but not for PSA or PAP.
Neg (not) Spec (partially) Regulation (positive) of CEA associated with adenocarcinoma
2) Confidence 0.38 Published 1999 Journal Urol. Int. Section Abstract Doc Link 10738193 Disease Relevance 1.14 Pain Relevance 0.08
In another group of 39 patients with metastatic breast cancer who received palliative therapy, a limited correlation was noted between the clinical course of the disease and changes in TPA and CEA values measured in linear fashion.
Regulation (values) of CEA associated with disease, advanced or metastatic breast cancer and palliative
3) Confidence 0.23 Published 1979 Journal J. Natl. Cancer Inst. Section Abstract Doc Link 292806 Disease Relevance 0.97 Pain Relevance 0.10
SNCG levels in colon adenocarcinoma were closely associated with intravascular embolus and tumor recurrence but independent of preoperative serum CEA levels.
Neg (independent) Regulation (independent) of CEA in colon associated with cancer, embolism, colon cancer and recurrence
4) Confidence 0.22 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2912867 Disease Relevance 1.09 Pain Relevance 0
There were no significant changes in tumor markers CEA and CA 15-3 during the treatment in both groups.
Neg (no) Regulation (changes) of CEA associated with cancer
5) Confidence 0.13 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2829500 Disease Relevance 0.10 Pain Relevance 0
After the 3-month break in therapy the CEA values increased to 5.6 ng/ml and after termination of the 9th therapy cycle the CEA value was 12.1 ng/ml (Figure 3B).
Regulation (value) of CEA
6) Confidence 0.10 Published 2009 Journal J Transl Med Section Body Doc Link PMC2714296 Disease Relevance 0.53 Pain Relevance 0
Another study in advanced thyroid cancer evaluated bispecific MAb (BsMAb), which targets both CEA and diethylenetriamine penta-acetic acid.
Regulation (targets) of CEA in thyroid associated with thyroid neoplasm
7) Confidence 0.08 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2723756 Disease Relevance 0.74 Pain Relevance 0
Another new treatment strategy is to target CEA, an antigen present on the surface of a majority of HNSCC tumors [31, 79], via MAb immunotherapy plus radiotherapy.
Regulation (target) of CEA associated with cancer
8) Confidence 0.05 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2723756 Disease Relevance 0.56 Pain Relevance 0
Vaccines of this type have shown potential for targeting CEA when recombinant fowlpox or ALVAC (canarypox) viruses, which do not replicate in human cells, are used as vectors, with and without GM-CSF [86, 87].
Regulation (targeting) of CEA associated with fowlpox
9) Confidence 0.05 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2723756 Disease Relevance 1.17 Pain Relevance 0.04
Durability has been increased by placing the CEA on a scaffolding of widely meshed autograft.315 Alternatively, CEA placed over deepithelialized allograft (ie, engrafted allodermis) has also proved successful.284
Regulation (placing) of CEA
10) Confidence 0.05 Published 2005 Journal Journal of Burns and Wounds Section Body Doc Link PMC1501116 Disease Relevance 0.62 Pain Relevance 0

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