INT192331

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.54
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (UBR7) ligase activity (UBR7) biological_process (UBR7)
Anatomy Link Frequency
endothelial cells 1
fibroblasts 1
UBR7 (Homo sapiens)
INSRR (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 54 97.78 Very High Very High Very High
Potency 6 57.16 Quite High
cytokine 10 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 12 98.48 Very High Very High Very High
Fibrosis 50 97.78 Very High Very High Very High
Pulmonary Fibrosis 18 71.52 Quite High
Disease 8 5.00 Very Low Very Low Very Low
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Pathologic Processes 2 5.00 Very Low Very Low Very Low
Second Primary Neoplasms 2 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the context of fibrosis development in conventional cancer therapy, including radio- and chemotherapy, we studied here the effects of SU9518, a receptor tyrosine kinase inhibitor of PDGF signaling on human primary dermal fibroblasts and endothelial cells.
SU9518 Negative_regulation (inhibitor) of receptor in fibroblasts associated with fibrosis and cancer
1) Confidence 0.00 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1458351 Disease Relevance 0.27 Pain Relevance 0.11
In the context of fibrosis development in conventional cancer therapy, including radio- and chemotherapy, we studied here the effects of SU9518, a receptor tyrosine kinase inhibitor of PDGF signaling on human primary dermal fibroblasts and endothelial cells.
SU9518 Negative_regulation (inhibitor) of receptor in endothelial cells associated with fibrosis and cancer
2) Confidence 0.00 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1458351 Disease Relevance 0.27 Pain Relevance 0.11

General Comments

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