INT192333

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Context Info
Confidence 0.11
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PDGFA, FN1) extracellular region (PDGFA, FN1) cell adhesion (FN1)
proteinaceous extracellular matrix (FN1) embryo development (PDGFA) cell-cell signaling (PDGFA)
Anatomy Link Frequency
HGF 2
PDGFA (Homo sapiens)
FN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 27 87.20 High High
chemokine 2 76.56 Quite High
Potency 4 62.76 Quite High
cINOD 3 47.84 Quite Low
corticosteroid 2 45.28 Quite Low
Inflammation 5 31.28 Quite Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 75 96.52 Very High Very High Very High
Hypoxia 15 96.24 Very High Very High Very High
Malignant Neoplastic Disease 4 94.92 High High
Shock 1 91.36 High High
Fibrosis 25 87.20 High High
Hyperplasia 1 81.00 Quite High
INFLAMMATION 9 47.44 Quite Low
Disease 6 43.68 Quite Low
Pulmonary Fibrosis 9 40.32 Quite Low
Metastasis 9 38.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, PDGF has been shown to stimulate the production of several matrix molecules, such as collagen, fibronectin, and proteoglycan [23-25].
PDGF Positive_regulation (stimulate) of Gene_expression (production) of fibronectin
1) Confidence 0.11 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1458351 Disease Relevance 0.43 Pain Relevance 0.11
mediators, such as VEGF, PDGF, bFGFs, angiopoetins, HGF, fibronectin, and
PDGF Positive_regulation (mediators) of Gene_expression (angiopoetins) of fibronectin in HGF
2) Confidence 0.04 Published 2008 Journal PPAR Research Section Body Doc Link PMC2366048 Disease Relevance 0.83 Pain Relevance 0.07

General Comments

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