INT192618

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Atrx) nucleus (Atrx) helicase activity (Atrx)
DNA binding (Atrx)
Atrx (Mus musculus)
Hba-a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 3 5.00 Very Low Very Low Very Low
Botox 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thalassemia 21 99.62 Very High Very High Very High
Syndrome 24 72.12 Quite High
Cryptorchidism 4 52.28 Quite High
Intellectual Impairment 14 50.00 Quite Low
Urogenital Abnormalities 2 48.08 Quite Low
Disease 7 29.12 Quite Low
Congenital Anomalies 23 5.00 Very Low Very Low Very Low
Convulsion 9 5.00 Very Low Very Low Very Low
Muscle Hypotonia 7 5.00 Very Low Very Low Very Low
Vomiting 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The fact that patients with identical mutations may have very different, albeit stable, degrees of alpha thalassaemia suggests that the effect of the ATRX protein on alpha globin expression may be modified by other genetic factors.


ATRX protein Regulation (effect) of Gene_expression (expression) of alpha globin associated with thalassemia
1) Confidence 0.08 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1464382 Disease Relevance 0.45 Pain Relevance 0

General Comments

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