INT192656

Context Info Confidence 0.04 First Reported 2006 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 2 Total Number 2 Disease Relevance 0.93 Pain Relevance 0.54

cell differentiation (EID1) nucleus (EID1) cell cycle (EID1) cytoplasm (EID1)

Anatomy Link Frequency smooth muscle cell 1 EID1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 7 80.08 backache 63 77.44 Acupuncture 79 75.00 Pain 20 5.00 Analgesic 12 5.00 visual analogue scale 7 5.00 cINOD 7 5.00 Percutaneous transluminal coronary angioplasty 6 5.00 diffuse noxious inhibitory control 3 5.00 analgesia 2 5.00

Disease Link Frequency Relevance Heat Retinoblastoma 1 100.00 Hyperplasia 4 82.76 INFLAMMATION 10 80.08 Injury 11 78.56 Low Back Pain 65 77.44 Cardiovascular Disease 46 77.28 Immunotherapy Of Cancer 1 55.20 Myocardial Infarction 4 46.92 Thrombosis 26 44.08 Pathologic Constriction 6 38.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This complex then increases cellular cyclin dependent kinase inhibitor (CDKI) p27 and inhibits the action of retinoblastoma protein (pRb), which regulates vascular smooth muscle cell proliferation (11, 13).

Negative_regulation (inhibits) of retinoblastoma protein in smooth muscle cell associated with retinoblastoma

1) Confidence 0.04 Published 2007 Journal McGill Journal of Medicine : MJM Section Body Doc Link PMC2323487 Disease Relevance 0.67 Pain Relevance 0.04

We define CRI as a reduction of 35% or more in the RMQ results.

Negative_regulation (reduction) of CRI

2) Confidence 0.01 Published 2006 Journal BMC Complement Altern Med Section Abstract Doc Link PMC1468427 Disease Relevance 0.26 Pain Relevance 0.50

General Comments

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