INT192748

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Context Info
Confidence 0.68
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.40
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (BCR) signal transduction (BCR) plasma membrane (BCR)
kinase activity (BCR)
Anatomy Link Frequency
mast cell 1
olfactory 1
BCR (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 4 83.44 Quite High
corticosteroid 3 71.72 Quite High
noradrenaline 1 70.96 Quite High
Central nervous system 1 68.64 Quite High
Glutamate 12 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
cva 5 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 20 99.06 Very High Very High Very High
Leukemia 6 98.96 Very High Very High Very High
Systemic Mastocytosis 12 98.26 Very High Very High Very High
Chronic Myelomonocytic Leukemia 15 97.48 Very High Very High Very High
Myelofibrosis 28 96.68 Very High Very High Very High
Hypereosinophilic Syndrome 14 96.10 Very High Very High Very High
Myelodysplastic Syndromes 60 95.36 Very High Very High Very High
Myeloproliferative Disorder 32 93.98 High High
Disease 50 76.56 Quite High
Neurodegenerative Disease 1 66.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MPDs (which include polycythemia vera (PV), essential thrombocythemia (ET), chronic eosinophilic leukemia (CEL), primary myelofibrosis (PMF), chronic myelomonocytic leukemia (CMML), and systemic mast cell disease (SMCD)) exclude chronic myeloid leukemia (CML) because of the pathognomic importance of the BCR-ABL translocation for the diagnosis and treatment of this disorder with imatinib mesylate.
Localization (translocation) of BCR in mast cell associated with leukemia, myeloid leukemia, myelofibrosis, myeloproliferative disorder, chronic myelomonocytic leukemia, hypereosinophilic syndrome, systemic mastocytosis and myelodysplastic syndromes
1) Confidence 0.68 Published 2007 Journal Biologics : Targets & Therapy Section Abstract Doc Link PMC2721304 Disease Relevance 2.25 Pain Relevance 0
Almost all of the most closely correlated tissue pairs were evolutionary or functionally related.
Localization (related) of all
2) Confidence 0.11 Published 2008 Journal BMC Biol Section Body Doc Link PMC2645369 Disease Relevance 0.14 Pain Relevance 0.18
However, the eight functional chicken olfactory genes that have been cloned so far—COR1–6, COR7a, and COR7b [66]—are all localized in close proximity on chicken Chromosome 5 and are not part of that expansion.
Localization (localized) of all in olfactory
3) Confidence 0.01 Published 2006 Journal PLoS Computational Biology Section Body Doc Link PMC1472694 Disease Relevance 0 Pain Relevance 0
All recombinant proteins were exported in the supernatant as predicted by specialized algorithms.
Localization (exported) of All
4) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2151134 Disease Relevance 0 Pain Relevance 0

General Comments

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