INT192861

Context Info Confidence 0.10 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.13 Pain Relevance 0

cell adhesion (Emb)

Emb (Mus musculus) Mela (Mus musculus)

Pain Link Frequency Relevance Heat Central nervous system 66 5.00 Spinal cord 6 5.00 anesthesia 2 5.00 Inflammation 2 5.00 glial activation 2 5.00 isoflurane 2 5.00

Disease Link Frequency Relevance Heat Infection 122 65.80 Leukemia 6 50.00 Neurodegenerative Disease 6 24.88 Stress 80 5.00 Disease 16 5.00 Death 2 5.00 Necrosis 2 5.00 Subacute Sclerosing Panencephalitis 2 5.00 Skin Cancer 2 5.00 INFLAMMATION 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Importantly, the primary Env protein species observed for both FrCasE and Fr57E infected microglial cultures was a high apparent molecular weight form of Env (gpr85) consistent with precursor protein, rather than the processed form (gp70) noted in 3T3 cells.

gp70 Binding (form) of Env

1) Confidence 0.10 Published 2006 Journal Retrovirology Section Body Doc Link PMC1475625 Disease Relevance 0.06 Pain Relevance 0

Importantly, the primary Env protein species observed for both FrCasE and Fr57E infected microglial cultures was a high apparent molecular weight form of Env (gpr85) consistent with precursor protein, rather than the processed form (gp70) noted in 3T3 cells.

gp70 Binding (species) of Env protein

2) Confidence 0.10 Published 2006 Journal Retrovirology Section Body Doc Link PMC1475625 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.