INT192919

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.39
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (MIER3) DNA binding (MIER3)
Anatomy Link Frequency
T98G 2
MIER3 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 4 55.76 Quite High
Disease Link Frequency Relevance Heat
Glioma 100 98.32 Very High Very High Very High
Apoptosis 356 97.76 Very High Very High Very High
Reprotox - General 1 4 97.40 Very High Very High Very High
Skin Cancer 4 95.76 Very High Very High Very High
Death 128 90.48 High High
Toxicity 12 89.44 High High
Fatigue 4 86.80 High High
Solid Tumor 4 83.88 Quite High
Cancer 96 80.44 Quite High
Leishmaniasis 4 67.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a first set of experiments cytotoxic efficacy of ErPC3 was evaluated in the most responsive T98G cells 48 h after treatment with the same drug concentrations as used for the ErPC-experiments (0, 12.5, 25 or 50 ?
Positive_regulation (efficacy) of ErPC3 in T98G
1) Confidence 0.03 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1475859 Disease Relevance 0.28 Pain Relevance 0
In contrast to the above mentioned drugs, ErPC and its derivative ErPC3 lack hemolytic side effects and thus constitute the first synthetic phospholipid analogs that are suited for intravenous administration.
Positive_regulation (derivative) of ErPC3
2) Confidence 0.03 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1475859 Disease Relevance 0.90 Pain Relevance 0.06
In our investigation we demonstrate for the first time that the prototypical intravenously applicable APC-derivatives ErPC and ErPC3 increase the radiation response of human malignant glioma cell lines.
Positive_regulation (derivatives) of ErPC3 associated with glioma
3) Confidence 0.03 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1475859 Disease Relevance 0.78 Pain Relevance 0
Similar to ErPC, its derivative ErPC3 turned out to be a potent inducer of growth arrest and apoptosis in T98G cells (Fig. 8A).
Positive_regulation (derivative) of ErPC3 in T98G associated with apoptosis
4) Confidence 0.03 Published 2006 Journal Radiat Oncol Section Body Doc Link PMC1475859 Disease Relevance 0.44 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox