INT192946

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.77
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PMAIP1) mitochondrion (PMAIP1) nucleus (PMAIP1)
PMAIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 23 99.06 Very High Very High Very High
Inflammation 20 92.16 High High
Inflammatory mediators 3 71.60 Quite High
Inflammatory response 3 50.00 Quite Low
peripheral neuropathy 13 5.00 Very Low Very Low Very Low
dexamethasone 10 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Serotonin 1 5.00 Very Low Very Low Very Low
tricyclic antidepressant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute-phase Reaction 11 100.00 Very High Very High Very High
Injury 4 99.82 Very High Very High Very High
Stress 14 99.68 Very High Very High Very High
Hypoxia 1 94.92 High High
INFLAMMATION 27 92.16 High High
Cardiovascular Disease 2 90.56 High High
Death 3 79.96 Quite High
Apoptosis 11 75.68 Quite High
Aging 8 66.88 Quite High
Endometriosis (extended) 1 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human NOXA contains one BH3 (Bcl-2 homology 3) domain, which has a high affinity for the antiapoptotic factor Mcl-1.
Gene_expression (contains) of NOXA
1) Confidence 0.27 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2990320 Disease Relevance 0.76 Pain Relevance 0
Within the cytokine networking during the surgical trauma-induced APR, IL-6 production is stimulated by the other two cytokines [13].
Gene_expression (production) of APR associated with acute-phase reaction, injury and cytokine
2) Confidence 0.20 Published 2006 Journal Immun Ageing Section Body Doc Link PMC1475883 Disease Relevance 1.01 Pain Relevance 0.52

General Comments

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