INT192960

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (KIT) extracellular space (KIT) plasma membrane (KIT)
nucleus (KIT) cytoplasm (KIT)
Anatomy Link Frequency
mast cell 4
KIT (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 99.72 Very High Very High Very High
Mast Cell Leukemia 2 98.32 Very High Very High Very High
Acute Myeloid Leukemia 6 97.52 Very High Very High Very High
Myeloproliferative Disorder 2 96.00 Very High Very High Very High
Gastrointestinal Stromal Tumor 18 93.92 High High
Lung Cancer 2 91.52 High High
Leiomyosarcoma 2 86.88 High High
Leukemia 2 86.08 High High
Obesity 11 84.72 Quite High
Malignant Fibrous Histiocytoma 2 79.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Singular CD117 expression or in combination with that of SCF is noted in several hematopoetic tumors including mast cell leukemia, acute myelogenous leukemia, and other myeloproliferative disorders [10].
Regulation (Singular) of Gene_expression (expression) of CD117 in mast cell associated with myeloproliferative disorder, cancer, acute myeloid leukemia and mast cell leukemia
1) Confidence 0.45 Published 2006 Journal Diagn Pathol Section Body Doc Link PMC1475889 Disease Relevance 1.89 Pain Relevance 0
Singular CD117 expression or in combination with that of SCF is noted in several hematopoetic tumors including mast cell leukemia, acute myelogenous leukemia, and other myeloproliferative disorders [10].
Regulation (noted) of Gene_expression (expression) of CD117 in mast cell associated with myeloproliferative disorder, cancer, acute myeloid leukemia and mast cell leukemia
2) Confidence 0.45 Published 2006 Journal Diagn Pathol Section Body Doc Link PMC1475889 Disease Relevance 1.91 Pain Relevance 0
MSC have been defined as the cells having plastic-adherence when maintained under standard culture conditions, must have the ability of osteogenic, adipogenic and chondrogenic differentiation, must express CD73, CD90, and CD105, and must lack expression of hematopoietic lineage markers c-kit, CD14, CD34, CD 45, CD 11b, CD 29, CD79?
Spec (must) Regulation (lack) of Gene_expression (expression) of c-kit
3) Confidence 0.15 Published 2010 Journal Stem Cells International Section Body Doc Link PMC3010655 Disease Relevance 0.36 Pain Relevance 0

General Comments

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