INT193067

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CHRM2) signal transducer activity (CHRM2)
Anatomy Link Frequency
lymphocytes 2
CHRM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 4 97.12 Very High Very High Very High
Inflammation 31 62.88 Quite High
Inflammatory mediators 4 50.96 Quite High
bradykinin 3 43.12 Quite Low
c fibre 2 17.36 Low Low
agonist 27 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 51 99.96 Very High Very High Very High
Asthma 39 99.78 Very High Very High Very High
Viral Infection 3 99.02 Very High Very High Very High
Occupational Lung Diseases 3 76.64 Quite High
Disease 13 68.64 Quite High
Hypersensitivity 4 64.16 Quite High
INFLAMMATION 36 62.88 Quite High
Airway Remodeling 17 5.00 Very Low Very Low Very Low
Hypertrophy 6 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Viral infections, which may play a role in both asthma and COPD, induce M2 dysfunction through neuraminidases that cleave portions of the M2 receptor, and through as yet incompletely characterized mechanisms involving macrophages, CD8+ lymphocytes, and possibly IFN-?
Positive_regulation (induce) of Transcription (portions) of M2 receptor in lymphocytes associated with asthma, pulmonary disease and viral infection
1) Confidence 0.03 Published 2006 Journal Respir Res Section Body Doc Link PMC1479816 Disease Relevance 1.03 Pain Relevance 0.13

General Comments

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