INT193069

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.15
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 4.06
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CD38) hydrolase activity, acting on glycosyl bonds (CD38) plasma membrane (CD38)
nucleus (CD38)
Anatomy Link Frequency
T lymphocyte 4
smooth muscle 2
CD38 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 41 99.90 Very High Very High Very High
Inflammation 113 99.70 Very High Very High Very High
agonist 27 97.36 Very High Very High Very High
Etanercept 6 77.20 Quite High
spastic colon 18 68.08 Quite High
abdominal pain 3 58.64 Quite High
depression 7 53.80 Quite High
headache 2 46.88 Quite Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 119 99.70 Very High Very High Very High
Chronic Fatigue Syndrome 150 96.28 Very High Very High Very High
Toxicity 28 96.24 Very High Very High Very High
Residual Neoplasm 12 95.48 Very High Very High Very High
Epstein-barr Virus 8 94.12 High High
Infection 38 91.56 High High
Chronic Lymphoid Leukemia 188 90.24 High High
Death 5 89.52 High High
Targeted Disruption 2 86.88 High High
Apoptosis 15 86.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immune activation is also suggested by an elevation of pro-inflammatory cytokines, an increased expression of T lymphocyte activation markers, such as CD26 and CD38 [12] and decreased function of natural killer (NK) cells (for review see [13]).
Positive_regulation (increased) of Gene_expression (expression) of CD38 in T lymphocyte associated with inflammation and cytokine
1) Confidence 0.15 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2964729 Disease Relevance 1.22 Pain Relevance 0.50
[32] can increase CD38 expression, ADP-ribosyl cyclase activity, and Ca2+ responses to cholinergic agonists in airway smooth muscle.
Positive_regulation (increase) of Gene_expression (expression) of CD38 in smooth muscle associated with agonist
2) Confidence 0.13 Published 2006 Journal Respir Res Section Body Doc Link PMC1479816 Disease Relevance 0.35 Pain Relevance 0.18
Also, the increased expression of CD38, which is found on early T-cell precursors and mature T cells upon mitogenic activation indicates a T-cell response [23].
Positive_regulation (increased) of Gene_expression (expression) of CD38 in T-cell
3) Confidence 0.11 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2491649 Disease Relevance 0.21 Pain Relevance 0.18
70 years, or those with adverse cytogenetics, unmutated IGHV genes or high expression of ZAP-70 or CD38 was observed.59
Positive_regulation (unmutated) of Gene_expression (observed.59) of CD38
4) Confidence 0.10 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004569 Disease Relevance 1.10 Pain Relevance 0.07
70 years, or those with adverse cytogenetics, unmutated IGHV genes or high expression of ZAP-70 or CD38 was observed.59
Positive_regulation (observed.59) of Gene_expression (observed.59) of CD38
5) Confidence 0.10 Published 2010 Journal Cancer management and research Section Body Doc Link PMC3004569 Disease Relevance 1.04 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox