INT193080

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ROCK1, Ppp1r14a) cytosol (ROCK1) signal transduction (ROCK1)
Golgi apparatus (ROCK1) cytoskeleton (ROCK1)
ROCK1 (Homo sapiens)
Ppp1r14a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 27 85.64 High High
Inflammation 31 66.72 Quite High
cytokine 4 41.40 Quite Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
bradykinin 3 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
c fibre 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 66.72 Quite High
Disease 13 65.12 Quite High
Asthma 39 50.00 Quite Low
Hypersensitivity 4 44.80 Quite Low
Targeted Disruption 2 30.92 Quite Low
Pulmonary Disease 51 5.00 Very Low Very Low Very Low
Airway Remodeling 17 5.00 Very Low Very Low Very Low
Hypertrophy 6 5.00 Very Low Very Low Very Low
Hyperplasia 4 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MLCP is also inhibited by binding to the phosphoprotein CPI-17, which is targeted for phosphorylation by both Rho kinase and PKC (see [37] for detailed review on the role of Rho-kinase in airway hyperresponsiveness).
Rho kinase Positive_regulation (targeted) of phosphoprotein CPI-17
1) Confidence 0.00 Published 2006 Journal Respir Res Section Body Doc Link PMC1479816 Disease Relevance 0.13 Pain Relevance 0.18

General Comments

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