INT193104

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2006
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.61
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Birc5) chromosome segregation (Birc5) intracellular (Birc5)
enzyme binding (Birc5) embryo development (Birc5) cytoplasm (Birc5)
Birc5 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 33 81.72 Quite High
COX-2 inhibitor 9 70.68 Quite High
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Osteoarthritis 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 255 93.92 High High
Repression 12 88.12 High High
Colon Cancer 15 85.76 High High
Death 30 85.48 High High
Breast Cancer 9 84.64 Quite High
Glioblastoma 36 83.72 Quite High
Lymphatic System Cancer 12 78.76 Quite High
Aneuploidy 3 77.20 Quite High
Apoptosis 135 76.64 Quite High
Reprotox - General 1 3 65.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Down-regulation of survivin is independent of p53
Neg (independent) Positive_regulation (independent) of Regulation (regulation) of survivin
1) Confidence 0.49 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1479836 Disease Relevance 0.83 Pain Relevance 0
Down-regulation of survivin is independent of cyclooxygenase-2
Neg (independent) Positive_regulation (independent) of Regulation (regulation) of survivin
2) Confidence 0.49 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1479836 Disease Relevance 0.47 Pain Relevance 0
To determine whether survivin expression was similarly affected by these drugs, we generated cells that were stably transfected with luciferase reporter constructs under the control of the survivin promoter.
Positive_regulation (transfected) of Regulation (control) of survivin
3) Confidence 0.45 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1479836 Disease Relevance 0.30 Pain Relevance 0.15

General Comments

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