INT19314

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Context Info
Confidence 0.35
First Reported 1991
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.93
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FSTL1) extracellular region (FSTL1)
Anatomy Link Frequency
dentate gyrus 1
FSTL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 4 97.52 Very High Very High Very High
fluoxetine 5 96.68 Very High Very High Very High
Nucleus accumbens 2 92.00 High High
Hippocampus 5 91.64 High High
Eae 1 90.84 High High
antidepressant 9 89.72 High High
lidocaine 1 88.32 High High
Serotonin 1 82.20 Quite High
depression 8 75.12 Quite High
Neuropeptide 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 6 98.78 Very High Very High Very High
Depressive Disorder 1 80.32 Quite High
Depression 8 75.12 Quite High
Neurodegenerative Disease 1 67.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increase in FRP and the decrease in MDF was most pronounced with the class-I-antiarrhythmic drugs, but these compounds showed the typical negative inotropic effects, too.
Positive_regulation (increase) of FRP
1) Confidence 0.35 Published 1991 Journal Arch. Pharm. (Weinheim) Section Abstract Doc Link 2043041 Disease Relevance 0 Pain Relevance 0.09
After 5 wk of running, cell proliferation increased in FSL but not in FRL rats.
Neg (not) Positive_regulation (increased) of FSL
2) Confidence 0.01 Published 2005 Journal Int. J. Neuropsychopharmacol. Section Abstract Doc Link 15769301 Disease Relevance 0.45 Pain Relevance 0.80
However, in other brain regions, fluoxetine administration caused a differential effect on the induction of NPY-related genes in the two rat strains: in the CA region and dentate gyrus NPY mRNA expression was increased in the FSL, but decreased in the FRL.
Positive_regulation (increased) of FSL in dentate gyrus associated with sprains and strains and fluoxetine
3) Confidence 0.01 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9729278 Disease Relevance 0.48 Pain Relevance 0.83

General Comments

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