INT193199

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Context Info
Confidence 0.60
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 4.55
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (RAPH1) plasma membrane (RAPH1) cytoskeleton (RAPH1)
cytoplasm (RAPH1)
Anatomy Link Frequency
nodules 1
RAPH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 7 83.20 Quite High
endometriosis 5 82.32 Quite High
agonist 5 66.96 Quite High
pain pelvic 15 40.48 Quite Low
imagery 14 5.00 Very Low Very Low Very Low
Spinal cord 10 5.00 Very Low Very Low Very Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 35 99.48 Very High Very High Very High
Sarcoma 10 99.04 Very High Very High Very High
Malignant Neoplastic Disease 25 96.96 Very High Very High Very High
Dislocations 12 90.72 High High
Recurrence 10 88.56 High High
Metastasis 15 86.76 High High
Uterine Hemorrhage 5 84.88 Quite High
Endometrial Cancer 5 84.44 Quite High
Carcinoma 20 83.52 Quite High
Pain 7 83.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bekkers hypothesized that LPD without exogenous or increased endogenous oestrogen exposure, and without expression of ER/PR by tumour cells, may represent a different entity carrying a higher risk of malignant transformation [3].
Gene_expression (expression) of LPD associated with malignant neoplastic disease and cancer
1) Confidence 0.60 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.91 Pain Relevance 0.03
The interval between initial detection of LPD and the development of sarcoma varies from synchronous diagnosis to 8 years.
Gene_expression (detection) of LPD associated with sarcoma
2) Confidence 0.46 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 1.02 Pain Relevance 0
Most patients with LPD present without specific symptoms and many documented cases of LPD have been discovered incidentally during surgery (caesarean section, laparotomy or laparoscopy).
Gene_expression (present) of LPD
3) Confidence 0.46 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.86 Pain Relevance 0.12
The identification of luteinizing hormone (LH) receptors in LPD nodules from a postmenopausal woman suggests that the typical postmenopausal increase in LH levels might affect the pathogenesis of this condition [22].
Gene_expression (nodules) of LPD in nodules
4) Confidence 0.46 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.60 Pain Relevance 0.09
Most patients with LPD present without specific symptoms and many documented cases of LPD have been discovered incidentally during surgery (caesarean section, laparotomy or laparoscopy).
Gene_expression (present) of LPD
5) Confidence 0.46 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.84 Pain Relevance 0.11
Likewise, reader 1's diagnostic values for grade 3 lesions were higher in patients with a first LPD compared to those with a recurrent LPD (Table 4).
Gene_expression (higher) of LPD
6) Confidence 0.09 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906436 Disease Relevance 0.16 Pain Relevance 0
Likewise, reader 1's diagnostic values for grade 3 lesions were higher in patients with a first LPD compared to those with a recurrent LPD (Table 4).
Gene_expression (higher) of LPD
7) Confidence 0.09 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2906436 Disease Relevance 0.16 Pain Relevance 0

General Comments

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