INT193255

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.40
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGER4) signal transducer activity (PTGER4)
Anatomy Link Frequency
eosinophil 1
PTGER4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 98.40 Very High Very High Very High
Inflammation 28 87.88 High High
Cannabinoid receptor 9 84.00 Quite High
Inflammatory stimuli 3 53.04 Quite High
agonist 2 35.36 Quite Low
aspirin 8 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Glutamate receptor 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 15 95.48 Very High Very High Very High
INFLAMMATION 34 87.88 High High
Chronic Sinusitis 24 84.80 Quite High
Nasal Polyps 24 82.96 Quite High
Neuroblastoma 3 82.52 Quite High
Rhinitis 16 72.08 Quite High
Polyps 3 22.44 Low Low
Asthma 7 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These studies also found evidence for secretin, prostacyclin, opioid and alpha2-adrenergic receptors In support of this we found significantly high levels of mRNA for Ptgir1, Ptger1, Ptger3, Ptger4, Oprd1, Oprl1 and Adra2b.
Transcription (levels) of Ptger4 associated with opioid
1) Confidence 0.19 Published 2011 Journal BMC Genomics Section Body Doc Link PMC3024950 Disease Relevance 0.08 Pain Relevance 0.14
This is on line with our findings however, mRNA levels of EP2 and EP4 receptors did not correlate with eosinophil number or eosinophil activation markers but it was increased in the disease groups compared to controls.
Transcription (levels) of EP4 in eosinophil associated with disease
2) Confidence 0.18 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 1.31 Pain Relevance 0.24

General Comments

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