INT193261

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Context Info
Confidence 0.28
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.14
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGER2) signal transducer activity (PTGER2)
Anatomy Link Frequency
structural cells 4
PTGER2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 16 99.12 Very High Very High Very High
Inflammation 96 93.76 High High
Inflammatory stimuli 7 91.80 High High
COX-2 inhibitor 23 64.56 Quite High
cINOD 6 48.56 Quite Low
metalloproteinase 102 8.40 Low Low
cytokine 76 5.00 Very Low Very Low Very Low
chemokine 22 5.00 Very Low Very Low Very Low
Inflammatory marker 6 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Herpes Simplex Virus 238 95.36 Very High Very High Very High
Asthma 14 94.48 High High
INFLAMMATION 112 93.76 High High
Hypoxia 1 81.08 Quite High
Infection 104 76.64 Quite High
Chronic Sinusitis 48 73.28 Quite High
Nasal Polyps 48 69.36 Quite High
Rhinitis 32 62.48 Quite High
Sarcoma 79 50.00 Quite Low
Cancer 20 21.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, a study comparing EP receptor expression in nasal biopsies from aspirin intolerant and tolerant patients showed an up-regulation of EP1 and EP2 in structural cells from aspirin intolerant subjects [15].
Positive_regulation (-) of Regulation (regulation) of EP2 in structural cells associated with aspirin
1) Confidence 0.28 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.72 Pain Relevance 0.34
More recently, a study comparing EP receptor expression in nasal biopsies from aspirin intolerant and tolerant patients showed an up-regulation of EP1 and EP2 in structural cells from aspirin intolerant subjects [15].
Positive_regulation (up) of Regulation (regulation) of EP2 in structural cells associated with aspirin
2) Confidence 0.28 Published 2006 Journal Respir Res Section Body Doc Link PMC1481584 Disease Relevance 0.72 Pain Relevance 0.34
Studies to decipher the molecular pathway of PGE2 mediated ORF73 promoter regulation and viral latency is under investigation.
Positive_regulation (mediated) of Regulation (regulation) of PGE2
3) Confidence 0.04 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 0.70 Pain Relevance 0.08

General Comments

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