INT193268

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.56
Pain Relevance 2.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Brs3) signal transducer activity (Brs3)
Anatomy Link Frequency
afferent neurons 1
Brs3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 240 100.00 Very High Very High Very High
c fibre 48 88.80 High High
sodium channel 19 79.36 Quite High
unmyelinated 6 77.96 Quite High
Central nervous system 6 74.88 Quite High
fibrosis 2 73.28 Quite High
depression 6 28.88 Quite Low
Action potential 34 5.00 Very Low Very Low Very Low
agonist 25 5.00 Very Low Very Low Very Low
Spinal cord 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bundle-branch Block 8 97.92 Very High Very High Very High
Disease 14 97.28 Very High Very High Very High
Stress 2 90.88 High High
Toxicity 3 83.04 Quite High
Heart Arrhythmia 20 77.92 Quite High
Heart Rate Under Development 20 77.80 Quite High
Recurrence 8 77.00 Quite High
Apoptosis 2 73.88 Quite High
Fibrosis 2 73.28 Quite High
Dilated Cardiomyopathy 6 66.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Such A-type BRs are likely typical of a broad association for cranial visceral afferent neurons with CAP sensitivity.
BRs Spec (likely) Binding (association) of in afferent neurons associated with qutenza
1) Confidence 0.03 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0.06 Pain Relevance 0.86
Despite these limitations of the single fiber BR recordings, the ADN ENG results bolster the association of C-type BRs with CAP sensitivity and A-type BRs with CAP resistance consistent with other studies [27].
BRs Binding (association) of associated with qutenza
2) Confidence 0.03 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0.14 Pain Relevance 0.83
Despite these limitations of the single fiber BR recordings, the ADN ENG results bolster the association of C-type BRs with CAP sensitivity and A-type BRs with CAP resistance consistent with other studies [27].
BRs Binding (association) of associated with qutenza
3) Confidence 0.03 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0.15 Pain Relevance 0.89
BrS is characterized by a typical ECG pattern of incomplete or complete right bundle branch block and ST segment elevation (?
BrS Binding (characterized) of associated with bundle-branch block
4) Confidence 0.02 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1592481 Disease Relevance 0.67 Pain Relevance 0.04
As of January 2006, approximately 160 SCN5A mutations had been reported[33], and approximately 65% of them are associated with a BrS phenotype, but no specific clustering within the coding region is demonstrable.
BrS Binding (associated) of
5) Confidence 0.02 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1592481 Disease Relevance 0.53 Pain Relevance 0.04

General Comments

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