INT193383

Context Info Confidence 0.35 First Reported 2006 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 7 Total Number 7 Disease Relevance 0.90 Pain Relevance 0.73

transmembrane transport (SLC43A3)

Anatomy Link Frequency brain 1 SLC43A3 (Homo sapiens)

Pain Link Frequency Relevance Heat Electroencephalography 145 100.00 gABA 15 96.88 alcohol 37 75.12 imagery 15 70.08 addiction 46 68.16 cerebral cortex 11 63.36 Opioid 6 53.12 drug abuse 4 46.24 cannabis 7 45.00 Raphe 3 41.28

Disease Link Frequency Relevance Heat Cognitive Disorder 60 97.08 Alcohol Addiction 36 82.32 Drug Dependence 22 68.16 Nicotine Addiction 6 62.64 Opiate Addiction 4 53.56 Drug Induced Neurotoxicity 10 50.00 Cannabis Dependence 1 45.44 Disease 6 27.44 Antisocial Personality Disorder 2 13.88 Depression 9 12.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Another site identified in the study of EEG phenotypes in Plains Indians was on chromosome 5 in a region between 53 and 114 cM.

Gene_expression (phenotypes) of EEG

1) Confidence 0.35 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2851592 Disease Relevance 0.32 Pain Relevance 0.15

Thomasius in his first major search for neurotoxic sequela in one-hundred and five long time Ecstasy users, of which our EEG recordings were obtained, found several neuropsychiatric sequela, which have been already published elsewhere [19].

Gene_expression (recordings) of EEG

2) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2990767 Disease Relevance 0.30 Pain Relevance 0.04

The definition of "A-waves" does not require that the waveform have oscillations with a period within the alpha-EEG range, although many A-waves at supraSTZ rates have had such oscillations.

Gene_expression (range) of EEG

3) Confidence 0.16 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1483834 Disease Relevance 0 Pain Relevance 0

Interesting, this phenomenon does not depend on the EEG alpha-activity expression, since it was identically present in subjects with very high and very low alpha-activity [40].

Gene_expression (expression) of EEG

4) Confidence 0.02 Published 2008 Journal The Open Neuroimaging Journal Section Body Doc Link PMC2695620 Disease Relevance 0.18 Pain Relevance 0

Among the different methodological strategies adopted to study the brain-mind complexity and its expression in the complexity of EEG signal, the so called “Operational Architectonics” (OA) framework [9,7,14,27,28] has received attention, especially due to its good compromise between simplicity, neurophysiologic accuracy, and cognitive plausibility.

Gene_expression (expression) of EEG in brain associated with cognitive disorder

5) Confidence 0.02 Published 2008 Journal The Open Neuroimaging Journal Section Body Doc Link PMC2695620 Disease Relevance 0.09 Pain Relevance 0

This theory of EEG is capable of producing the main features of spontaneous human EEG and is able to account quantitatively and qualitatively for the effects that GABA enhancing anaesthetics and sedatives have on the EEG.

Gene_expression (producing) of EEG associated with gaba and electroencephalography

6) Confidence 0.01 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.27

This theory of EEG is capable of producing the main features of spontaneous human EEG and is able to account quantitatively and qualitatively for the effects that GABA enhancing anaesthetics and sedatives have on the EEG.

Gene_expression (producing) of EEG associated with gaba and electroencephalography

7) Confidence 0.01 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.27

General Comments

This test has worked.