INT1934

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 1976
Last Reported 2010
Negated 3
Speculated 3
Reported most in Abstract
Documents 68
Total Number 74
Disease Relevance 60.56
Pain Relevance 10.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Cys1) cilium (Cys1) molecular_function (Cys1)
biological_process (Cys1) cytoplasm (Cys1)
Anatomy Link Frequency
muscle 8
plasma 5
chest 4
blood 2
myocardium 1
Cys1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 75 99.92 Very High Very High Very High
anesthesia 57 99.88 Very High Very High Very High
ischemia 4 99.50 Very High Very High Very High
Pain 15 99.10 Very High Very High Very High
Inflammatory response 7 98.78 Very High Very High Very High
Bioavailability 2 98.72 Very High Very High Very High
Inflammation 118 98.56 Very High Very High Very High
abdominal pain 4 98.22 Very High Very High Very High
isoflurane 7 98.12 Very High Very High Very High
Electroencephalography 1 96.88 Very High Very High Very High
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 163 100.00 Very High Very High Very High
Cramps 32 100.00 Very High Very High Very High
Congenital Anomalies 31 99.96 Very High Very High Very High
Myocardial Infarction 298 99.92 Very High Very High Very High
Angina 32 99.92 Very High Very High Very High
Rigor 1 99.92 Very High Very High Very High
Toxicity 186 99.90 Very High Very High Very High
Muscle Weakness 48 99.90 Very High Very High Very High
Cv General 2 Under Development 11 99.64 Very High Very High Very High
Necrosis 24 99.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, increased plasma MB CPK activity may be considered a reliable index of myocardial infarction in patients undergoing cardiac catheterization.
Positive_regulation (increased) of CPK in plasma associated with myocardial infarction
1) Confidence 0.68 Published 1976 Journal Cathet Cardiovasc Diagn Section Abstract Doc Link 1000620 Disease Relevance 0.38 Pain Relevance 0
In contrast, 100 control patients with acute myocardial infarction exhibited peak total CPK activity averaging 0.833 +/- 0.037 (SD), and MB CPK was elevated in all cases (0.078 +/- 0.027 (SD) IU/ml).
Positive_regulation (elevated) of CPK associated with myocardial infarction
2) Confidence 0.68 Published 1976 Journal Cathet Cardiovasc Diagn Section Abstract Doc Link 1000620 Disease Relevance 0.42 Pain Relevance 0
Four percent of participants in each treatment group experienced elevations in creatine phosphokinase (CPK), alanine aminotransferase (ALT), or aspartate aminotransferase (AST).
Positive_regulation (elevations) of CPK associated with disorders of creatine metabolism
3) Confidence 0.67 Published 2010 Journal European Heart Journal Section Body Doc Link PMC2821630 Disease Relevance 1.12 Pain Relevance 0
An elevation of total serum CPK was found in three patients; however, only one of these patients had an elevated (positive) CPK-MB isoenzyme fraction.
Positive_regulation (elevated) of CPK associated with disorders of creatine metabolism
4) Confidence 0.65 Published 1996 Journal Pediatr Emerg Care Section Abstract Doc Link 8677169 Disease Relevance 0.95 Pain Relevance 0.09
An elevation of total serum CPK was found in three patients; however, only one of these patients had an elevated (positive) CPK-MB isoenzyme fraction.
Positive_regulation (elevation) of CPK associated with disorders of creatine metabolism
5) Confidence 0.65 Published 1996 Journal Pediatr Emerg Care Section Abstract Doc Link 8677169 Disease Relevance 0.96 Pain Relevance 0.09
Monitoring of serum CPK enzymes during CAN therapy is warranted until further studies have determined the significance of elevated CPK-MB isoenzymes in otherwise asymptomatic children treated for severe status asthmaticus.
Spec (determined) Positive_regulation (elevated) of CPK associated with disorders of creatine metabolism and status asthmaticus
6) Confidence 0.65 Published 1996 Journal Pediatr Emerg Care Section Abstract Doc Link 8677169 Disease Relevance 1.08 Pain Relevance 0.08
We report a case of a 47-year-old woman with a typical clinical pain, a ST elevation in lateral EKG leads and an increase of the CPK-MB enzymes serum level suggesting the diagnosis of an acute lateral myocardial infarction.
Positive_regulation (increase) of CPK-MB in lateral associated with pain and myocardial infarction
7) Confidence 0.59 Published 1999 Journal Rev Med Liege Section Abstract Doc Link 10081304 Disease Relevance 0.60 Pain Relevance 0.10
The definitive criteria of AMI were: typical chest pain, electrocardiographic findings, and plasma CPK-MB elevation.
Positive_regulation (elevation) of CPK-MB in plasma associated with angina and myocardial infarction
8) Confidence 0.58 Published 1990 Journal Cardiologia Section Abstract Doc Link 2245425 Disease Relevance 1.49 Pain Relevance 0.19
The early mortality was 2.88 percent, 7.69 percent of patients showed elevation in CPK-MB, while 5.76 percent had a rise in Troponin 'T' and 2 percent of patients showed ECG changes.
Positive_regulation (elevation) of CPK-MB
9) Confidence 0.57 Published 1996 Journal Indian Heart J Section Abstract Doc Link 8908826 Disease Relevance 0.42 Pain Relevance 0.25
Accordingly, we studied 111 patients with unstable angina to determine whether exclusion of patients with initially elevated MB CPK improves the perioperative mortality rate.
Spec (whether) Positive_regulation (elevated) of MB CPK associated with angina
10) Confidence 0.52 Published 1977 Journal J. Thorac. Cardiovasc. Surg. Section Abstract Doc Link 299905 Disease Relevance 0.49 Pain Relevance 0.31
Of the 111 patients, 16, with initially elevated MB CPK activity, were excluded and managed medically.
Positive_regulation (elevated) of MB CPK
11) Confidence 0.52 Published 1977 Journal J. Thorac. Cardiovasc. Surg. Section Abstract Doc Link 299905 Disease Relevance 0.48 Pain Relevance 0.37
Elevated plasma MB CPK isoenzyme activity is a remarkably sensitive and specific marker of myocardial damage.
Positive_regulation (Elevated) of MB CPK in plasma
12) Confidence 0.52 Published 1977 Journal J. Thorac. Cardiovasc. Surg. Section Abstract Doc Link 299905 Disease Relevance 0.44 Pain Relevance 0.26
In contrast, 100 control patients with acute myocardial infarction exhibited peak total CPK activity averaging 0.833 +/- 0.037 (SD), and MB CPK was elevated in all cases (0.078 +/- 0.027 (SD) IU/ml).
Positive_regulation (elevated) of CPK associated with myocardial infarction
13) Confidence 0.49 Published 1976 Journal Cathet Cardiovasc Diagn Section Abstract Doc Link 1000620 Disease Relevance 0.44 Pain Relevance 0
In the bacteremia/endocarditis trial 5 of 22 patients who received prior or concomitant HMG-CoA reductase inhibitors and daptomycin developed creatine phosphokinase (CPK) elevations of >500 U/L.
Positive_regulation (elevations) of CPK associated with disorders of creatine metabolism, bacteremia and cv unclassified under development
14) Confidence 0.49 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2374935 Disease Relevance 1.01 Pain Relevance 0.14
A combination of sevoflurane anesthesia and succinylcholine might cause a significant increase in the serum CPK level.
Spec (might) Positive_regulation (increase) of serum CPK associated with anesthesia
15) Confidence 0.46 Published 1994 Journal Masui Section Abstract Doc Link 8164331 Disease Relevance 0.08 Pain Relevance 0.62
In three remaining patients, MB CPK was elevated and myocardial infarction was confirmed by 99mTc (SN) pyrophosphate scan.
Positive_regulation (elevated) of CPK associated with myocardial infarction
16) Confidence 0.46 Published 1976 Journal Cathet Cardiovasc Diagn Section Abstract Doc Link 1000620 Disease Relevance 0.54 Pain Relevance 0.06
Thus, CPK elevations after catheterization reflect release of enzyme from noncardiac sources rather than from injured myocardium.
Positive_regulation (elevations) of CPK in myocardium
17) Confidence 0.46 Published 1976 Journal Cathet Cardiovasc Diagn Section Abstract Doc Link 1000620 Disease Relevance 0.36 Pain Relevance 0
All immunological tests were negative and the specific cause of the eosinophilia was unknown. 2 weeks after admission, she complained of severe chest pain suddenly and her ECG showed ST elevation on V1-4 and serum CPK level was elevated to 290 IU/l.
Positive_regulation (elevation) of serum CPK in chest associated with angina and eosinophilia
18) Confidence 0.46 Published 1989 Journal Kokyu To Junkan Section Abstract Doc Link 2616922 Disease Relevance 1.64 Pain Relevance 0.17
A moderate increase (by 10%) in the creatine phosphokinase (CPK) was also reported by these authors.


Positive_regulation (increase) of CPK associated with disorders of creatine metabolism
19) Confidence 0.45 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.35 Pain Relevance 0.08
In the dalcetrapib group, CPK elevations >3 × upper limit of normal (ULN) were observed in 2% (2/89) of participants and CPK elevations >5 × ULN in 1% (1/89) of participants; also with elevated levels at baseline (>1 but <3 × ULN).
Positive_regulation (elevations) of CPK in upper associated with disorders of creatine metabolism
20) Confidence 0.45 Published 2010 Journal European Heart Journal Section Body Doc Link PMC2821630 Disease Relevance 1.12 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox