INT193504

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Context Info
Confidence 0.58
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 7.44
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (OPN1SW) plasma membrane (OPN1SW) signal transducer activity (OPN1SW)
OPN1SW (Homo sapiens)
Pain Link Frequency Relevance Heat
behavioral therapy 28 100.00 Very High Very High Very High
Pain 43 98.32 Very High Very High Very High
depression 198 98.28 Very High Very High Very High
spastic colon 84 93.24 High High
sSRI 19 83.44 Quite High
tolerance 1 76.44 Quite High
antidepressant 30 75.40 Quite High
Lasting pain 6 62.96 Quite High
Dismenorea 72 46.12 Quite Low
alcohol 16 19.76 Low Low
Disease Link Frequency Relevance Heat
Post-traumatic Stress Disorder 168 100.00 Very High Very High Very High
Injury 150 100.00 Very High Very High Very High
Traumatic Stress Disorders 2 100.00 Very High Very High Very High
Sleep Disorders 117 99.98 Very High Very High Very High
Premenstrual Syndrome 412 99.84 Very High Very High Very High
Musculoskeletal Disease 2 99.82 Very High Very High Very High
Anxiety Disorder 135 99.80 Very High Very High Very High
Pain 48 98.32 Very High Very High Very High
Depression 327 98.28 Very High Very High Very High
Cognitive Disorder 79 97.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our program was designed to use the forest environment as a mediator of CBT by facilitating patients to reflect their problems and try to reconstruct cognitive error after strolling in the forest or hearing stories about trees.
Positive_regulation (mediator) of CBT associated with cognitive disorder
1) Confidence 0.58 Published 2009 Journal Psychiatry Investigation Section Body Doc Link PMC2808793 Disease Relevance 0.37 Pain Relevance 0.09
Given the importance of parental involvement in the treatment of other child anxiety disorders, yet the lack of examination of this issue in the treatment of youth PTSD (overall), there is also a need to examine whether CBT interventions can be enhanced through the addition of a parent-based component.
Positive_regulation (enhanced) of CBT associated with post-traumatic stress disorder and anxiety disorder
2) Confidence 0.43 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2998467 Disease Relevance 1.09 Pain Relevance 0
A comparison of the two active treatment conditions will test whether the efficacy of CBT for PTSD following accidental injury can be enhanced with parent involvement.
Positive_regulation (enhanced) of CBT associated with post-traumatic stress disorder and injury
3) Confidence 0.43 Published 2010 Journal BMC Psychiatry Section Body Doc Link PMC2998467 Disease Relevance 0.20 Pain Relevance 0
In addition to using CBT to address these specific clinical issues, CBT is also used to address resistance to mindfulness practice such as issues with acceptance of pain.
Positive_regulation (using) of CBT associated with pain and behavioral therapy
4) Confidence 0.43 Published 2008 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2249749 Disease Relevance 0.33 Pain Relevance 1.04
This is the same reason why rehabilitation is continuously needed after acute musculoskeletal disease, or why CBT to treat avoidance symptoms in post-traumatic stress disorder is required even after physical symptoms have improved through use of medications.
Positive_regulation (required) of CBT associated with musculoskeletal disease and traumatic stress disorders
5) Confidence 0.39 Published 2009 Journal Psychiatry Investigation Section Body Doc Link PMC2808793 Disease Relevance 0.55 Pain Relevance 0.03
The increase in the reported use of CBT in the MoodGYM condition is to be expected since CBT formed the core of the intervention and participants knew CBT was offered in their intervention.
Positive_regulation (increase) of CBT
6) Confidence 0.32 Published 2006 Journal BMC Psychiatry Section Body Doc Link PMC1501008 Disease Relevance 0.26 Pain Relevance 0.13
It is hypothesized that CBT will be more effective for this group of patients, because CBT is generally considered to be the treatment of choice for anxiety disorders.
Positive_regulation (effective) of CBT associated with anxiety disorder
7) Confidence 0.27 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC2174932 Disease Relevance 0.40 Pain Relevance 0
Although a later study [105] failed to replicate these results, the authors described a decreased amplitude during the LP within PMDD patients, as well as a trend for increased nocturnal CBT in PMDD women compared to controls during the LP.
Positive_regulation (increased) of CBT associated with premenstrual syndrome
8) Confidence 0.13 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0.80 Pain Relevance 0
An early study showed that, compared to healthy controls, PMDD women had significantly elevated nocturnal CBT and a reduced CBT amplitude during the LP [104].
Positive_regulation (elevated) of CBT associated with premenstrual syndrome
9) Confidence 0.13 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0.97 Pain Relevance 0
Most notably, during the LP compared to the FP, there is an increase of ~0.3–0.4°C in CBT levels (Figure 4) [35, 36] as well as a significant reduction in the amplitude of the circadian variation of CBT [35–38], owing mainly to a blunted nocturnal decline of CBT.
Positive_regulation (increase) of CBT
10) Confidence 0.13 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 0.16 Pain Relevance 0
Producing changes in the proper direction to correct for altered rhythms in PMDD, early-SD delayed rhythms of CBT and TSH, and decreased PRL amplitude, while late-SD increased CBT amplitude, delayed TSH and decreased PRL; however it also advanced rhythms of CBT, PRL, and cortisol (not favorable).
Positive_regulation (increased) of CBT associated with sleep disorders and premenstrual syndrome
11) Confidence 0.13 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2817387 Disease Relevance 1.15 Pain Relevance 0.04
E-health applications providing CBT for anxiety are a potential solution to poor access to services.
Positive_regulation (providing) of CBT associated with anxiety disorder
12) Confidence 0.12 Published 2010 Journal Trials Section Body Doc Link PMC2878300 Disease Relevance 0.69 Pain Relevance 0.14

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