INT193550

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Context Info
Confidence 0.29
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ephb1) signal transduction (Ephb1) extracellular region (Bdnf)
cytoplasmic membrane-bounded vesicle (Bdnf) plasma membrane (Ephb1) cytoplasm (Ephb1)
Anatomy Link Frequency
brain 2
Ephb1 (Rattus norvegicus)
Bdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 5 87.92 High High
cytokine 2 61.00 Quite High
Sciatic nerve 15 10.52 Low Low
allodynia 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nervous System Injury 7 89.36 High High
Wallerian Degeneration 2 64.88 Quite High
Injury 7 48.20 Quite Low
Mycobacterium Infection 1 40.72 Quite Low
Ganglion Cysts 1 8.04 Low Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the neuronal cell bodies, at least one study has demonstrated that ERK was required for an upregulated expression of brain-derived neurotrophic factor (BDNF) following axotomy [13] and BDNF can accelerate axonal regeneration [21,22].
ERK Positive_regulation (required) of Gene_expression (expression) of BDNF in brain
1) Confidence 0.29 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1501035 Disease Relevance 0.30 Pain Relevance 0.14

General Comments

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