INT193676

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.31
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prdx2) mitochondrion (Prdx2) oxidoreductase activity (Prdx2)
cytoplasm (Prdx2)
Prdx2 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 4 66.08 Quite High
sodium channel 6 53.12 Quite High
Calcium channel 8 49.92 Quite Low
antagonist 1 17.28 Low Low
tolerance 20 5.00 Very Low Very Low Very Low
cytokine 19 5.00 Very Low Very Low Very Low
Inflammation 14 5.00 Very Low Very Low Very Low
Neuropathic pain 9 5.00 Very Low Very Low Very Low
dorsal root ganglion 7 5.00 Very Low Very Low Very Low
nav1.3 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroma 79 99.68 Very High Very High Very High
Stress 55 96.48 Very High Very High Very High
Disease 7 84.60 Quite High
Cancer 55 83.84 Quite High
Necrosis 7 68.32 Quite High
Parkinson's Disease 1 66.64 Quite High
Pain 4 66.08 Quite High
Apoptosis 36 48.72 Quite Low
Epilepsy 1 48.60 Quite Low
Breast Cancer 5 47.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, the increased expression of peroxiredoxin 2 during neuroma formation was also confirmed, as was vimentin expression.
Positive_regulation (increased) of Gene_expression (expression) of peroxiredoxin 2 associated with neuroma
1) Confidence 0.06 Published 2008 Journal Mol Pain Section Body Doc Link PMC2525634 Disease Relevance 0.83 Pain Relevance 0.09
Overexpression of thioredoxin reductase (TrxR) increases growth rates and resistance to cytotoxic agents that induce oxidative stress [109,110].
Positive_regulation (Overexpression) of Gene_expression (Overexpression) of thioredoxin reductase associated with stress
2) Confidence 0.02 Published 2006 Journal Theor Biol Med Model Section Body Doc Link PMC1508139 Disease Relevance 0.48 Pain Relevance 0

General Comments

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