INT193821

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 2.80
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
nucleus 2
pr (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 12 7.36 Low Low
Inflammation 9 5.00 Very Low Very Low Very Low
palliative 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
carbamazepine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
anticonvulsant 3 5.00 Very Low Very Low Very Low
peripheral neuropathy 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 136 100.00 Very High Very High Very High
Toxicity 50 99.44 Very High Very High Very High
Metastasis 19 97.92 Very High Very High Very High
Leiomyosarcoma 13 96.88 Very High Very High Very High
Skin Cancer 4 90.04 High High
Sarcoma 49 87.88 High High
Cancer 125 71.76 Quite High
Malignant Fibrous Histiocytoma 12 63.04 Quite High
Adenocarcinoma 1 51.52 Quite High
Congenital Anomalies 4 43.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activity as expressed by a PR by CA-125 and/or RECIST criteria was three times higher in the subgroup of patients with PFI ?
Positive_regulation (by) of Gene_expression (expressed) of PR
1) Confidence 0.24 Published 2010 Journal Annals of Oncology Section Body Doc Link PMC2844948 Disease Relevance 0.25 Pain Relevance 0
Similarly, the proportion of patients with PR or disease stabilization was much higher among patients with a PFI ?
Positive_regulation (higher) of Gene_expression (proportion) of PR associated with disease
2) Confidence 0.21 Published 2010 Journal Annals of Oncology Section Body Doc Link PMC2844948 Disease Relevance 0.31 Pain Relevance 0
Similarly, the proportion of patients with PR or disease stabilization was much higher among patients with a PFI ?
Positive_regulation (stabilization) of Gene_expression (proportion) of PR associated with disease
3) Confidence 0.21 Published 2010 Journal Annals of Oncology Section Body Doc Link PMC2844948 Disease Relevance 0.31 Pain Relevance 0
In these systems, keratin promoters are used to restrict the expression of the RU486 inducible Cre recombinase-PR fusion protein; upon treatment with the RU486 activator, the Cre recombinase-PR fusion protein translocates to the nucleus and excises sequences between Lox P sites, facilitating conditional genetic manipulation of target genes 22.
Positive_regulation (restrict) of Gene_expression (expression) of PR in nucleus
4) Confidence 0.12 Published 2010 Journal International Journal of Biological Sciences Section Body Doc Link PMC2815352 Disease Relevance 0.34 Pain Relevance 0
2 PR, 1 NC, and 1 progression were seen leading to an
Positive_regulation (leading) of Gene_expression (seen) of PR
5) Confidence 0.03 Published 2006 Journal Sarcoma Section Body Doc Link PMC1510952 Disease Relevance 1.58 Pain Relevance 0

General Comments

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