INT193837

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.85
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Aplp1) cell adhesion (Aplp1) Golgi apparatus (Aplp1)
plasma membrane (Aplp1) extracellular matrix organization (Aplp1) cytoplasm (Aplp1)
Anatomy Link Frequency
synapse 1
Aplp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 8 55.00 Quite High
Nav1.6 1 33.44 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
ischemia 7 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Peripheral nervous system 6 5.00 Very Low Very Low Very Low
sodium channel 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 77 96.88 Very High Very High Very High
Injury 7 93.12 High High
Stress 32 92.56 High High
Cerebrovascular Disease 3 87.08 High High
Targeted Disruption 45 84.16 Quite High
Cognitive Disorder 21 67.28 Quite High
Alzheimer's Dementia 35 65.72 Quite High
INFLAMMATION 14 54.76 Quite High
Death 7 36.44 Quite Low
Apoptosis 19 32.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
clearance (LRP; [241]), synapse formation (APP, APLP1, APLP2; [242,243]), neuroprotection (secreted APP ectodomain; reviewed in [244]) and immune functions (PSGL-1, ST6Gal I and IL-1R2; [160,161,164]).
Localization (secreted) of APLP1 in synapse
1) Confidence 0.45 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2211305 Disease Relevance 1.10 Pain Relevance 0
In vitro studies show that transcription from neprilysin gene promoter can be activated by cytosolic domains released from APP, APLP1 or APLP2 by ?
Localization (released) of APLP1
2) Confidence 0.37 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1513131 Disease Relevance 0.75 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox