INT1939

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Context Info
Confidence 0.73
First Reported 1977
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 5.90
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Cys1) cilium (Cys1) molecular_function (Cys1)
biological_process (Cys1) cytoplasm (Cys1)
Anatomy Link Frequency
myocardium 1
heart 1
Cys1 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 3 94.40 High High
Pain 4 89.92 High High
halothane 3 87.40 High High
Angina 2 85.24 High High
ischemia 40 80.48 Quite High
anesthesia 3 75.00 Quite High
fibrosis 3 56.72 Quite High
headache 5 44.96 Quite Low
depression 1 25.12 Quite Low
imagery 7 22.08 Low Low
Disease Link Frequency Relevance Heat
Disease 59 100.00 Very High Very High Very High
Cyst 32 100.00 Very High Very High Very High
Disorders Of Creatine Metabolism 25 100.00 Very High Very High Very High
Cramps 4 99.90 Very High Very High Very High
Injury 18 99.76 Very High Very High Very High
Rhabdomyolysis 3 99.24 Very High Very High Very High
Disease Progression 8 99.08 Very High Very High Very High
Dyspnea 2 98.88 Very High Very High Very High
Muscle Weakness 7 98.72 Very High Very High Very High
Toxicity 27 98.32 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, signs of rhabdomyolysis, in the absence of trauma, were also reported (CPK 41600 IU/mL; myoglobin 8300 IU/mL).
Localization (reported) of CPK associated with disorders of creatine metabolism, injury and rhabdomyolysis
1) Confidence 0.73 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1885285 Disease Relevance 1.38 Pain Relevance 0.05
Several spontaneous mouse models of PKD, such as cpk, bpk and orpk, resemble human recessive disease with respect to cyst localization and the rapid rate of disease progression (Table 1).
Localization (localization) of cpk associated with cyst, disease and disease progression
2) Confidence 0.20 Published 2007 Journal Cell Mol Life Sci Section Body Doc Link PMC2775119 Disease Relevance 1.26 Pain Relevance 0
In this model, ischemic myocardium treated with IGF-1 had significantly lesser amounts of detectable CPK than did myocardium treated with TNF-?
Localization (treated) of CPK in myocardium associated with disorders of creatine metabolism
3) Confidence 0.19 Published 2003 Journal Crit Care Section Body Doc Link PMC374373 Disease Relevance 1.04 Pain Relevance 0.10
The second most common cause was toxicity, which affected two (10.5%) and five (25.0%) patients (acute cardiomyopathy after 28 cycles ; muscular toxicity ; muscular weakness and CPK elevation, a combination of musculoskeletal cramps and CPK elevation ; a combination of grade 2 dyspnea, bronchial spams and atrial fibrillation ; three non-plitidepsin-related deaths).
Localization (elevation) of CPK associated with cramps, toxicity, disorders of creatine metabolism, muscle weakness, arrhythmias 2 under development, dyspnea and coronary heart disease
4) Confidence 0.08 Published 2009 Journal Marine Drugs Section Body Doc Link PMC2666889 Disease Relevance 1.09 Pain Relevance 0
Sustained release of heart-specific CPK-MB isoenzyme occurred in 78 percent of surviving patients.
Localization (release) of CPK-MB in heart
5) Confidence 0.05 Published 1977 Journal Anesth. Analg. Section Abstract Doc Link 301724 Disease Relevance 0.18 Pain Relevance 0.28
Biochemical tests were within normal range (SGOT, SGPT, gamma-GT, ALP, conjugated and unconjugated bilirubin, LDH, CPK, amylase).
Localization (amylase) of CPK
6) Confidence 0.04 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC2075501 Disease Relevance 0.94 Pain Relevance 0.21

General Comments

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