INT193950

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Notch1) extracellular space (Alph1) Golgi apparatus (Notch1)
plasma membrane (Notch1) nucleus (Notch1) embryo development (Notch1)
Anatomy Link Frequency
Notch 2
Alph1 (Mus musculus)
Notch1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 1 28.28 Quite Low
cINOD 2 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 11 66.24 Quite High
Adhesions 5 20.20 Low Low
Disease 63 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 5 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An independent C. elegans genetic screen identified aph-1 and pen-2 as enhancers of sel-12/Presenilin function, and showed that aph-2, aph-1 and pen-2 are required for Notch signaling, PS1 accumulation, and ?
aph-1 Positive_regulation (required) of Positive_regulation (accumulation) of Notch in Notch
1) Confidence 0.01 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1513131 Disease Relevance 0.07 Pain Relevance 0

General Comments

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