INT193957

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Bcl2l1, Psen2) mitochondrion (Bcl2l1) Golgi apparatus (Psen2)
endoplasmic reticulum (Psen2) intracellular (Bcl2l1) embryo development (Psen2)
Bcl2l1 (Mus musculus)
Psen2 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 2 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 63 98.42 Very High Very High Very High
Apoptosis 5 97.48 Very High Very High Very High
Stress 1 70.40 Quite High
Urological Neuroanatomy 1 55.40 Quite High
Targeted Disruption 11 40.96 Quite Low
Adhesions 5 18.08 Low Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low
Frontotemporal Dementia 5 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, it is unclear at present whether an increased apoptotic response associated with the expression of FAD-linked PS variants noted in several studies can be attributed to differential interaction of mutant PS1 or PS2 with Bcl-XL.
Bcl-XL Binding (interaction) of PS2 associated with disease and apoptosis
1) Confidence 0.07 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1513131 Disease Relevance 0.66 Pain Relevance 0

General Comments

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