INT193973

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK1) mitochondrion (MAPK1) Golgi apparatus (MAPK1)
DNA binding (MAPK1) protein complex (MAPK1) response to stress (MAPK1)
Anatomy Link Frequency
MDCK 2
TRGC1 (Homo sapiens)
MAPK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 16 87.40 High High
Cancer 5 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Fibrosarcoma 3 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Chronic Disease 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Sarcoma 1 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The C1 extract specifically reduced the activation of ERK1/2 without affecting the degree of phosphorylation of MEK1/2 on two other transformed cell lines HT-1080 and MSV-MDCK-INV cells.
C1 Negative_regulation (reduced) of Positive_regulation (activation) of ERK1/2 in MDCK
1) Confidence 0.01 Published 2006 Journal Evidence-based Complementary and Alternative Medicine Section Body Doc Link PMC1513146 Disease Relevance 0.09 Pain Relevance 0

General Comments

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