INT19422

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Context Info
Confidence 0.86
First Reported 1986
Last Reported 1991
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RIPK2) signal transduction (RIPK2) intracellular (RIPK2)
cytoplasm (RIPK2) signal transducer activity (RIPK2)
RIPK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 1 100.00 Very High Very High Very High
Cholecystokinin 2 97.08 Very High Very High Very High
Enkephalin 4 96.04 Very High Very High Very High
spastic colon 6 91.16 High High
Disease Link Frequency Relevance Heat
Constipation 1 93.28 High High
Diarrhoea 1 92.64 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

4 91.16 High High
Functional Bowel Disorder 2 87.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of CCK-8 reached in the peripheral circulation and degradation of the peptide in vitro and in vivo were used to evaluate metabolism of cholecystokinin.
Protein_catabolism (degradation) of CCK associated with cholecystokinin
1) Confidence 0.86 Published 1991 Journal Am. J. Physiol. Section Abstract Doc Link 2058671 Disease Relevance 0.35 Pain Relevance 0.60
At variance, the native peptides CCK8, substance P, neurotensin, and angiotensin II are not cleaved by the DAP.
Neg (not) Protein_catabolism (cleaved) of CCK8 associated with substance p
2) Confidence 0.00 Published 1986 Journal Biochemistry Section Abstract Doc Link 3814577 Disease Relevance 0 Pain Relevance 0.37

General Comments

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