INT19423

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Context Info
Confidence 0.70
First Reported 1987
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 6.05
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (REG3A) extracellular space (REG3A) extracellular region (REG3A)
cytoplasm (REG3A)
Anatomy Link Frequency
pancreas 2
hip 1
muscle 1
acinar cell 1
REG3A (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 11 99.96 Very High Very High Very High
backache 1 99.56 Very High Very High Very High
ketamine 7 99.04 Very High Very High Very High
Catecholamine 6 84.84 Quite High
Pain 1 82.08 Quite High
imagery 48 81.20 Quite High
Versed 5 75.80 Quite High
Osteoarthritis 2 75.00 Quite High
analgesia 1 75.00 Quite High
Analgesic 3 63.92 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 33 100.00 Very High Very High Very High
Disease 10 99.96 Very High Very High Very High
Low Back Pain 1 99.56 Very High Very High Very High
Adenocarcinoma 15 98.84 Very High Very High Very High
Injury 2 98.44 Very High Very High Very High
Fibrosis 1 97.36 Very High Very High Very High
Cancer 36 95.68 Very High Very High Very High
Pancreatic Cancer 59 94.28 High High
Metastasis 4 89.16 High High
Pain 1 82.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pancreatitis-associated protein (PAP) is almost absent in normal pancreas, but is strongly induced in acute pancreatitis.
Positive_regulation (induced) of PAP in pancreas associated with pancreatitis
1) Confidence 0.70 Published 2003 Journal Dig. Dis. Sci. Section Abstract Doc Link 12757156 Disease Relevance 1.01 Pain Relevance 0.07
Pancreatitis-associated protein (PAP) is almost absent in normal pancreas, but is strongly induced in acute pancreatitis.
Positive_regulation (induced) of Pancreatitis-associated protein in pancreas associated with pancreatitis
2) Confidence 0.61 Published 2003 Journal Dig. Dis. Sci. Section Abstract Doc Link 12757156 Disease Relevance 1.01 Pain Relevance 0.07
The index for hip disease (ISH) was established, validated and appraised as a new assessment test for the trial of new drugs as well as for long-term follow-up of patients, and to help with future indications for surgery.
Positive_regulation (index) of hip in hip associated with disease
3) Confidence 0.49 Published 1987 Journal Scand. J. Rheumatol. Suppl. Section Abstract Doc Link 3479839 Disease Relevance 0.51 Pain Relevance 0.12
Therefore we suggest that ELISA measurements of serum HIP/HAP and MUC-1 levels could be added to a panel of tests for the routine screening of population to identify individuals at increased risk for the developing pancreatic carcinoma.
Positive_regulation (measurements) of HIP associated with pancreatic cancer
4) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2776527 Disease Relevance 1.03 Pain Relevance 0.21
Overexpression of pancreatitis-associated protein (PAP) in human pancreatic ductal adenocarcinoma.
Positive_regulation (Overexpression) of PAP associated with adenocarcinoma and pancreatitis
5) Confidence 0.47 Published 2003 Journal Dig. Dis. Sci. Section Title Doc Link 12757156 Disease Relevance 1.43 Pain Relevance 0.15
In time course, PAP increased by about 5 mmHg in the ketamine group but not in the fentanyl group (P = 0.009).
Neg (not) Positive_regulation (increased) of PAP associated with ketamine
6) Confidence 0.45 Published 1991 Journal Anaesthesist Section Abstract Doc Link 2058827 Disease Relevance 0.14 Pain Relevance 0.72
Low back pain patients demonstrate increased hip extensor muscle activity during standardized submaximal rotation efforts.
Positive_regulation (increased) of hip in muscle associated with low back pain and backache
7) Confidence 0.45 Published 2006 Journal Spine Section Title Doc Link 17172991 Disease Relevance 0.10 Pain Relevance 0.10
Pancreatitis-associated protein (PAP), an acute-phase protein, is dramatically upregulated during acute and chronic pancreatitis.
Positive_regulation (upregulated) of Pancreatitis-associated protein associated with chronic pancreatitis
8) Confidence 0.26 Published 2009 Journal Pancreatology Section Abstract Doc Link 19077460 Disease Relevance 0.47 Pain Relevance 0.20
Pancreatitis-associated protein (PAP), a secretory acute-phase protein of the pancreatic acinar cell, is highly up-regulated early in acute pancreatitis.
Positive_regulation (up-regulated) of PAP in acinar cell associated with pancreatitis
9) Confidence 0.22 Published 2001 Journal Pancreas Section Abstract Doc Link 11249074 Disease Relevance 0.36 Pain Relevance 0

General Comments

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