INT194257

Context Info Confidence 0.15 First Reported 2006 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 5 Total Number 5 Disease Relevance 2.01 Pain Relevance 1.82

plasma membrane (Gpr182) cellular_component (Gpr182) signal transducer activity (Gpr182)

Gpr182 (Rattus norvegicus)

Pain Link Frequency Relevance Heat narcan 266 99.94 opiate 84 97.28 withdrawal 22 87.36 Pain 10 86.84 alcohol 20 83.52 methadone 27 75.72 headache 2 52.28 addiction 16 42.68 drug abuse 24 26.72 cocaine 9 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 30 93.60 Graves' Ophthalmopathy 1 92.24 Pain 7 86.84 Diabetes Mellitus 2 86.00 Overdose 166 85.28 Chills 2 78.96 Fever 2 78.52 Disease 7 68.56 Phobia 25 63.04 Emergencies 11 61.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Now, prostheses are becoming "smart", with MEMS sensors to detect changes and actuators to adjust prostheses.

Now Binding (becoming) of

1) Confidence 0.15 Published 2008 Journal Yonsei Medical Journal Section Body Doc Link PMC2628030 Disease Relevance 0.27 Pain Relevance 0

As one participant noted, after naloxone, "Now you're ill again, so you gotta get MORE money to get high, 'cause now you're sick!"

Now Binding (again) of associated with narcan

2) Confidence 0.09 Published 2006 Journal Harm Reduct J Section Body Doc Link PMC1557479 Disease Relevance 0.74 Pain Relevance 0.89

As one participant noted, after naloxone, "Now you're ill again, so you gotta get MORE money to get high, 'cause now you're sick!"

now Binding (get) of associated with narcan

3) Confidence 0.09 Published 2006 Journal Harm Reduct J Section Body Doc Link PMC1557479 Disease Relevance 0.72 Pain Relevance 0.81

You have been making a great personal effort to succeed but now it is time to engage others so that you can modify your environment and succeed even when your resolve fails.

now Binding (engage) of

4) Confidence 0.03 Published 2007 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC1805747 Disease Relevance 0 Pain Relevance 0

She is at a point right now where she is a little, you know, emotional, especially after hearing about that, you know what I'm saying?

now Binding (point) of

5) Confidence 0.02 Published 2006 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC1524736 Disease Relevance 0.28 Pain Relevance 0.12

General Comments

This test has worked.