INT194285

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Context Info
Confidence 0.54
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.03
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NCAM1) cell adhesion (NCAM1) plasma membrane (NCAM1)
Anatomy Link Frequency
solitary tract nucleus 3
macrophages 2
synapses 1
NCAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
vagus nerve 4 84.84 Quite High
Raphe 10 73.76 Quite High
Serotonin 2 73.28 Quite High
Neuropathic pain 4 71.76 Quite High
Inflammation 9 58.76 Quite High
trigeminal ganglion 30 50.00 Quite Low
medulla 26 50.00 Quite Low
Spinal cord 2 20.44 Low Low
Dorsal horn 2 19.96 Low Low
Hippocampus 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 3 90.84 High High
Influenza Virus Infection 22 87.04 High High
Frailty 2 75.68 Quite High
Neuropathic Pain 4 71.76 Quite High
Nociception 2 70.16 Quite High
Ganglion Cysts 38 61.24 Quite High
Hypersensitivity 1 60.96 Quite High
INFLAMMATION 10 58.76 Quite High
Adhesions 8 50.00 Quite Low
Stress 4 47.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the rat solitary tract nucleus, the overall PSA-NCAM expression decreases during the first two postnatal weeks and persists only at synapses in the adult [40].
Negative_regulation (decreases) of Gene_expression (expression) of PSA-NCAM in solitary tract nucleus
1) Confidence 0.54 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2612005 Disease Relevance 0.34 Pain Relevance 0.21
In the rat solitary tract nucleus, the overall PSA-NCAM expression decreases during the first two postnatal weeks and persists only at synapses in the adult [40].
Negative_regulation (persists) of in synapses Gene_expression (expression) of PSA-NCAM in solitary tract nucleus
2) Confidence 0.39 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2612005 Disease Relevance 0.34 Pain Relevance 0.22
For screening of h4Ph, CD 68 and CD56 expression the primary antibodies were diluted in 0.1 M Na-phosphate buffer, pH 7.0, containing 0,5% protease-free bovine serum albumin.
Negative_regulation (screening) of Gene_expression (expression) of CD56
3) Confidence 0.21 Published 2006 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1524763 Disease Relevance 0 Pain Relevance 0
Identity of the cell infiltrates was determined with a combination of haematoxylin staining and immunohistochemistry staining for CD68 (macrophages), CD3 (T cells), CD56 (NK cells) and CD20 (B cell) after antigen retrieval using microwave and citrate or EDTA buffer methods [14].
Spec (determined) Negative_regulation (combination) of Gene_expression (macrophages) of CD56 in macrophages
4) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2872666 Disease Relevance 0.35 Pain Relevance 0.03

General Comments

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