INT194333

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Racgap1) transport (Racgap1) mitochondrion (MFN2)
intracellular (Racgap1) embryo development (Racgap1) GTPase activity (MFN2)
Anatomy Link Frequency
tails 1
MFN2 (Homo sapiens)
Racgap1 (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 4 5.00 Very Low Very Low Very Low
Peripheral nervous system 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Charcot Marie Tooth Disease 20 58.16 Quite High
Mouth Disease 4 57.04 Quite High
Neuropathy 7 50.00 Quite Low
Disease 5 49.80 Quite Low
Peripheral Neuropathy 6 5.00 Very Low Very Low Very Low
Frailty 3 5.00 Very Low Very Low Very Low
Paresis 2 5.00 Very Low Very Low Very Low
Foot Deformities 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Optic Atrophy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analysis of MFN2 deletion constructs revealed that GTPase-dependent interaction between the N-terminal and C-terminal tails of MFN2 through their coiled-coil domains and a highly conserved domain in the most N-terminal region is essential for mitochondrial fusion [18].
MFN2 Binding (interaction) of GTPase in tails
1) Confidence 0.01 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1524942 Disease Relevance 0.38 Pain Relevance 0

General Comments

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