INT194396

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (CALCA, CALCA) intracellular (CALCA, CALCA) cell-cell signaling (CALCA, CALCA)
cytoplasm (CALCA, CALCA) extracellular space (CALCA, CALCA) extracellular region (CALCA, CALCA)
CALCA (Homo sapiens)
CALCA (Homo sapiens)
MTCP1NB (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 196 100.00 Very High Very High Very High
antagonist 10 84.16 Quite High
Neuropeptide 30 83.08 Quite High
agonist 11 36.96 Quite Low
headache 1 12.16 Low Low
Migraine 1 11.76 Low Low
Potency 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 35.16 Quite Low
Heat Stress Disorders 1 26.20 Quite Low
Reperfusion Injury 1 24.04 Low Low
Heart Disease 1 19.20 Low Low
Hypertension 1 18.36 Low Low
Increased Venous Pressure Under Development 2 13.44 Low Low
Migraine Disorders 1 12.16 Low Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, conservative substitution of F37 for tyrosine, which adds only one hydroxyl group to the phenol ring, again causes a significant loss of binding affinity, supporting the idea that CGRP-F37 is essential for high affinity interaction with the mature receptor protein [17].
CGRP-F37 Positive_regulation (essential) of CGRP-F37 Binding (interaction) of mature receptor protein associated with calcitonin gene-related peptide
1) Confidence 0.01 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1525162 Disease Relevance 0 Pain Relevance 0.51

General Comments

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