INT194405

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Context Info
Confidence 0.16
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (RAMP1) extracellular space (RAMP1) plasma membrane (RAMP1)
nucleus (DCLK3) cytoplasm (DCLK3)
DCLK3 (Homo sapiens)
RAMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 196 98.96 Very High Very High Very High
Neuropeptide 30 94.24 High High
Potency 14 25.00 Low Low
agonist 11 5.00 Very Low Very Low Very Low
antagonist 10 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 92.72 High High
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Migraine Disorders 1 5.00 Very Low Very Low Very Low
Reperfusion Injury 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Heat Stress Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies on the calcitonin-like receptor (CLR), which requires co-expression of the receptor-activity-modifying protein-1 (RAMP1) to function as a CGRP receptor, have shown an 18 amino acid N-terminus sequence important for binding CGRP.
CLR Positive_regulation (requires) of Gene_expression (expression) of receptor-activity-modifying protein-1 associated with calcitonin gene-related peptide
1) Confidence 0.16 Published 2006 Journal BMC Pharmacol Section Abstract Doc Link PMC1525162 Disease Relevance 0.09 Pain Relevance 0.43

General Comments

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