INT194407

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MTCP1NB) aging (CALCA) intracellular (CALCA)
cell-cell signaling (CALCA) cytoplasm (CALCA) cell proliferation (MTCP1NB)
CALCA (Homo sapiens)
MTCP1NB (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 196 100.00 Very High Very High Very High
antagonist 10 84.16 Quite High
Neuropeptide 30 83.08 Quite High
agonist 11 36.96 Quite Low
headache 1 12.16 Low Low
Migraine 1 11.76 Low Low
Potency 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 35.16 Quite Low
Heat Stress Disorders 1 26.20 Quite Low
Reperfusion Injury 1 24.04 Low Low
Heart Disease 1 19.20 Low Low
Hypertension 1 18.36 Low Low
Increased Venous Pressure Under Development 2 13.44 Low Low
Migraine Disorders 1 12.16 Low Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, conservative substitution of F37 for tyrosine, which adds only one hydroxyl group to the phenol ring, again causes a significant loss of binding affinity, supporting the idea that CGRP-F37 is essential for high affinity interaction with the mature receptor protein [17].
CGRP-F37 Binding (interaction) of mature receptor protein associated with calcitonin gene-related peptide
1) Confidence 0.01 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1525162 Disease Relevance 0 Pain Relevance 0.51

General Comments

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