INT194410

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CALCA, LZTS1) nucleus (CALCA, LZTS1) nucleoplasm (LZTS1)
aging (CALCA) Golgi apparatus (LZTS1) intracellular (CALCA)
CALCA (Homo sapiens)
LZTS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 196 100.00 Very High Very High Very High
Neuropeptide 30 99.24 Very High Very High Very High
agonist 11 52.24 Quite High
Potency 14 6.24 Low Low
antagonist 10 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low
Neuroblastoma 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Migraine Disorders 1 5.00 Very Low Very Low Very Low
Reperfusion Injury 1 5.00 Very Low Very Low Very Low
Stroke 1 5.00 Very Low Very Low Very Low
Heat Stress Disorders 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the lack of CGRP(1–36) or CGRP(1–19) affinity value changes for mutant compared to wild type CLRs, suggests that N-terminus leucines at positions 24 and 34 on the receptor might be interacting with F37 of the endogenous neuropeptide.


CGRP Spec (might) Binding (interacting) of F37 associated with neuropeptide and calcitonin gene-related peptide
1) Confidence 0.06 Published 2006 Journal BMC Pharmacol Section Body Doc Link PMC1525162 Disease Relevance 0 Pain Relevance 0.67

General Comments

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