INT194469

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.29
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apob) extracellular space (Apob) endoplasmic reticulum (Apob)
enzyme binding (Apob) lipid metabolic process (Apob)
Anatomy Link Frequency
plasma 1
Apob (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 62.60 Quite High
Inflammation 40 62.20 Quite High
agonist 2 62.00 Quite High
alcohol 3 55.24 Quite High
psoriasis 63 50.00 Quite Low
Angina 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
drug abuse 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipidemia 14 99.24 Very High Very High Very High
Psoriasis 106 97.24 Very High Very High Very High
Disorder Of Lipid Metabolism 52 95.84 Very High Very High Very High
Obesity 24 84.60 Quite High
Atherosclerotic Plaque 28 76.76 Quite High
Nicotine Addiction 4 76.16 Quite High
Syndrome 2 73.04 Quite High
Myocardial Infarction 7 72.96 Quite High
Atherosclerosis 78 68.56 Quite High
Targeted Disruption 3 68.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In most studies, elevated levels of apoA1, apoB [16, 43], apoC3, and apoE [41, 76–78] were detected in the serum of psoriatic patients compared to the healthy control group.
Positive_regulation (elevated) of apoB associated with psoriasis
1) Confidence 0.15 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2914266 Disease Relevance 1.08 Pain Relevance 0.03
T+294C SNP is associated with elevated plasma LDL cholesterol and apoB levels in men and we show in this work that similar associations are operating in women, we also looked for a potential gene-to-gene interaction between PPAR?
Positive_regulation (elevated) of apoB in plasma
2) Confidence 0.14 Published 2006 Journal International Journal of Medical Sciences Section Body Doc Link PMC1525216 Disease Relevance 0.64 Pain Relevance 0.03
sequences within ApoB have been identified and shown to be necessary for retaining
Positive_regulation (sequences) of ApoB
3) Confidence 0.10 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.57 Pain Relevance 0.06

General Comments

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