INT194472

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.71
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apob) extracellular space (Apob) endoplasmic reticulum (Apob)
enzyme binding (Apob) lipid metabolic process (Apob)
Anatomy Link Frequency
plasma 2
Caco-2 2
Apob (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 84.36 Quite High
fibrosis 32 81.44 Quite High
agonist 2 62.00 Quite High
abdominal pain 1 47.04 Quite Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 30 100.00 Very High Very High Very High
Diabetes Mellitus 2 95.88 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

1 94.00 High High
Obesity 18 84.60 Quite High
INFLAMMATION 3 84.36 Quite High
Cystic Fibrosis 32 81.44 Quite High
Hyperlipidemia 9 77.64 Quite High
Targeted Disruption 2 68.40 Quite High
Appetite Loss 2 57.04 Quite High
Coronary Artery Disease 16 53.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
T+294C SNP is associated with elevated plasma LDL cholesterol and apoB levels in men and we show in this work that similar associations are operating in women, we also looked for a potential gene-to-gene interaction between PPAR?
Positive_regulation (elevated) of Gene_expression (levels) of apoB in plasma
1) Confidence 0.15 Published 2006 Journal International Journal of Medical Sciences Section Body Doc Link PMC1525216 Disease Relevance 0.64 Pain Relevance 0.03
As demonstrated previously, CFTR depletion in Caco-2/15 cells has led to the enhancement of apolipoprotein B biosynthesis and the assembly of CM.
Positive_regulation (enhancement) of Gene_expression (biosynthesis) of apolipoprotein B in Caco-2 associated with disorder of lipid metabolism
2) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0.98 Pain Relevance 0.19

General Comments

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