INT194658

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Context Info
Confidence 0.45
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCL5) aging (CCL5) extracellular region (CCL5)
cell-cell signaling (CCL5) cytoplasm (CCL5)
Anatomy Link Frequency
synovial cells 2
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 50 96.96 Very High Very High Very High
rheumatoid arthritis 9 90.08 High High
chemokine 53 88.48 High High
Inflammation 32 82.00 Quite High
methotrexate 14 36.20 Quite Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 40 96.96 Very High Very High Very High
Rheumatoid Arthritis 9 90.08 High High
Arthritis 10 89.60 High High
INFLAMMATION 31 82.00 Quite High
Disease 10 40.32 Quite Low
Coagulation Disorder 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Peritonitis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to CCL3 and CXCL10, levels of transcription of mRNA for CCL5 were clearly increased in synovial cells, predominantly in CD8+ T cells, in all three subtypes of JIA investigated.
Positive_regulation (increased) of Transcription (transcription) of CCL5 in synovial cells associated with arthritis
1) Confidence 0.45 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526593 Disease Relevance 0.68 Pain Relevance 0.44

General Comments

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