INT194675

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.33
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK14, CREB1) signal transduction (MAPK14, CREB1) nucleus (MAPK14, CREB1)
mitochondrion (CREB1) response to stress (MAPK14) cytoplasm (MAPK14)
MAPK14 (Homo sapiens)
CREB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 68 24.48 Low Low
Inflammation 60 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 12 100.00 Very High Very High Very High
Shock 4 43.28 Quite Low
INFLAMMATION 62 5.00 Very Low Very Low Very Low
Autoimmune Disease 28 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Hypersensitivity 14 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Asthma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mitogen- and stress-activated kinase 1 and 2 (MSK1/2), for example, can directly activate transcription factors such as cAMP-response element-binding protein (CREB), activating transcription factor 1 (ATF1), NF-?
stress-activated kinase Positive_regulation (activate) of CREB associated with stress
1) Confidence 0.07 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0.17 Pain Relevance 0
Mitogen- and stress-activated kinase 1 and 2 (MSK1/2), for example, can directly activate transcription factors such as cAMP-response element-binding protein (CREB), activating transcription factor 1 (ATF1), NF-?
stress-activated kinase Positive_regulation (activate) of cAMP-response element-binding protein associated with stress
2) Confidence 0.07 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0.16 Pain Relevance 0

General Comments

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