INT194744

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Context Info
Confidence 0.49
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Stat4) signal transduction (Stat4) nucleus (Stat4)
DNA binding (Stat4) cytoplasm (Stat4) signal transducer activity (Stat4)
Stat4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 44 98.72 Very High Very High Very High
cytokine 57 89.16 High High
Multiple sclerosis 24 73.60 Quite High
Inflammation 65 65.76 Quite High
Central nervous system 48 59.28 Quite High
Spinal cord 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Demyelination 5 5.00 Very Low Very Low Very Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 36 96.36 Very High Very High Very High
Disease 69 86.80 High High
Autoimmune Disease 18 84.96 Quite High
Thymoma 1 76.76 Quite High
Demyelinating Disease 30 73.60 Quite High
INFLAMMATION 72 65.76 Quite High
Targeted Disruption 7 63.76 Quite High
Stroke 13 61.04 Quite High
Central Nervous System Disease 5 8.96 Low Low
Injury 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-12-induced tyrosine phosphorylation of Jak2, Tyk2, Stat3, and Stat4 in T
Phosphorylation (phosphorylation) of Stat4
1) Confidence 0.49 Published 2008 Journal PPAR Research Section Body Doc Link PMC2490815 Disease Relevance 0.76 Pain Relevance 0.22
Stimulation by IL-12, for example, induces STAT4 phosphorylation at both tyrosine and serine residues.
Phosphorylation (phosphorylation) of STAT4
2) Confidence 0.21 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526596 Disease Relevance 0.08 Pain Relevance 0.09

General Comments

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